Slc2a2 - solute carrier family 2 (facilitated glucose transporter), member 2 Gene

中文名称：溶质载体家族 2 (易化葡萄糖转运蛋白) ，成员 2

种属: Mus musculus

同用名: Glut2; Glut-2

关于 Slc2a2

功能概要

该基因编码的蛋白可启动 D-葡萄糖跨膜转运蛋白活性和脱氢抗坏血酸跨膜转运蛋白活性。参与脱氢抗坏血酸转运和葡萄糖跨膜转运。位于几种细胞成分中，包括顶端质膜；画笔边框；和细胞间连接。以多种结构表达，包括消化系统；早孕;肝;后肾;和睾丸。用于研究 2 型糖尿病。该基因的人类直系同源物与 Fanconi 综合征有关；糖原贮积病；和 2 型糖尿病。与人类 SLC2A2（溶质载体家族 2 成员 2）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables D-glucose transmembrane transporter activity and dehydroascorbic acid transmembrane transporter activity. Involved in dehydroascorbic acid transport and glucose transmembrane transport. Located in several cellular components, including apical plasma membrane; brush border; and cell-cell junction. Is expressed in several structures, including alimentary system; early conceptus; liver; metanephros; and testis. Used to study type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in Fanconi syndrome; glycogen storage disease; and type 2 diabetes mellitus. Orthologous to human SLC2A2 (solute carrier family 2 member 2). [provided by Alliance of Genome Resources, Apr 2022]