2. Gene
  3. Sp3 - trans-acting transcription factor 3 Gene

Sp3 - trans-acting transcription factor 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: D130027J01Rik

基因 ID: 20687 | 基因类型: protein coding

关于 Sp3

功能概要

This gene product belongs to a family of Sp1 related transcription factors, which regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses transcription of numerous genes. Alternative splicing results in transcript variants encoding different isoforms, and one variant initiates translation from a non-AUG (AUA) codon. [provided by RefSeq, Jul 2008]

Sp3 基因产物(2)

mRNA Protein Name
NM_001018042.3 NP_001018052.1 transcription factor Sp3 isoform 1
NM_001098425.1 NP_001091895.1 transcription factor Sp3 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
14630713 MGI
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
17130167 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
15094381 MGI
enables RNA polymerase II-specific DNA-binding transcription factor binding IPI
IPI: 通过物理相互作用推断
17130167 MGI
enables chromatin binding IDA
IDA: 通过直接分析推断
15522233 MGI
enables cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
15511642 MGI
enables double-stranded DNA binding IDA
IDA: 通过直接分析推断
15282343 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
20385708 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within B cell differentiation IMP
IMP: 通过突变表型推断
12676787 MGI
acts upstream of or within T cell differentiation IMP
IMP: 通过突变表型推断
12676787 MGI
acts upstream of or within definitive hemopoiesis IGI
IGI: 通过遗传相互作用推断
17584888 MGI
acts upstream of or within embryonic camera-type eye morphogenesis IGI
IGI: 通过遗传相互作用推断
17584888 MGI
acts upstream of or within embryonic placenta development IGI
IGI: 通过遗传相互作用推断
17584888 MGI
acts upstream of or within embryonic process involved in female pregnancy IGI
IGI: 通过遗传相互作用推断
17584888 MGI
acts upstream of or within embryonic skeletal system development IGI
IGI: 通过遗传相互作用推断
17584888 MGI
acts upstream of or within enucleate erythrocyte differentiation IGI
IGI: 通过遗传相互作用推断
17584888 MGI
acts upstream of or within erythrocyte differentiation IMP
IMP: 通过突变表型推断
12676787 MGI
acts upstream of or within granulocyte differentiation IMP
IMP: 通过突变表型推断
12676787 MGI
acts upstream of or within in utero embryonic development IGI
IGI: 通过遗传相互作用推断
17584888 MGI
acts upstream of or within liver development IGI
IGI: 通过遗传相互作用推断
17584888 MGI
acts upstream of or within lung development IGI
IGI: 通过遗传相互作用推断
17584888 MGI
acts upstream of or within megakaryocyte differentiation IGI
IGI: 通过遗传相互作用推断
17584888 MGI
acts upstream of or within monocyte differentiation IMP
IMP: 通过突变表型推断
12676787 MGI
acts upstream of or within myeloid progenitor cell differentiation IGI
IGI: 通过遗传相互作用推断
17584888 MGI
acts upstream of or within natural killer cell differentiation IMP
IMP: 通过突变表型推断
12676787 MGI
involved in negative regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
17130167 MGI
acts upstream of or within ossification IGI
IGI: 通过遗传相互作用推断
17584888 MGI
acts upstream of or within trophectodermal cell differentiation IGI
IGI: 通过遗传相互作用推断
17584888 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
15282343 MGI
part of transcription repressor complex IDA
IDA: 通过直接分析推断
17130167 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

transcription factor Sp3

相关产品

Pre-clinical Phase
生物活性分子 (9)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-161794A SP3N hydrochloride Degrader 99.84% 否
HY-161794 SP3N Degrader / 否
HY-RS13606 SP3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-125400 Zaragozic acid C / 否
HY-161795 SP3CHO / 否
HY-173132 AKR1Cs-IN-1 Inhibitor / 否
HY-180813 RORγ-IN-3 Inhibitor / 否
HY-RS18594 Sp3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25079 Sp3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sp3 NCBI NCBI:6670
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