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  2. Pde12 - phosphodiesterase 12 Gene

Pde12 - phosphodiesterase 12 Gene

中文名称:磷酸二酯酶 12

种属: Mus musculus

同用名: 2-PDE; 2'-PDE; E430028B21Rik

基因 ID: 211948 | 基因类型: protein coding

关于 Pde12

Chromosome 14: 26,381,113-26,391,038 reverse strand.GRCm39:CM001007.3

This gene has 1 transcript (splice variant), 204 orthologues, 5 paralogues and is associated with 6 phenotypes. Ubiquitous expression in thymus adult (RPKM 1.), ovary adult (RPKM 8.2) and 28 other tissues.

功能概要

预测该基因编码的蛋白可启动 3'-5'-核糖核酸外切酶活性。预计参与多个过程,包括RNA代谢过程;对细胞因子刺激的细胞反应;和调节线粒体 mRNA 的稳定性。预测作用于 mRNA 加工的上游或内部。位于线粒体中。在大脑中表达;前肠;泌尿生殖系统;和皮肤。与人 PDE12(磷酸二酯酶 12)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable 3'-5'-exoribonuclease activity. Predicted to be involved in several processes, including RNA metabolic process; cellular response to cytokine stimulus; and regulation of mitochondrial mRNA stability. Predicted to act upstream of or within mRNA processing. Located in mitochondrion. Is expressed in brain; foregut; genitourinary system; and skin. Orthologous to human PDE12 (phosphodiesterase 12). [provided by Alliance of Genome Resources, Apr 2022]

Pde12 基因产物(1)

mRNA Protein Name
NM_178668.4 NP_848783.3 2',5'-phosphodiesterase 12

Pde12 蛋白结构

EEP

EEP: cl00490 (297 - 606)

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  • 500
  • 608 a.a.
蛋白主名 其他名称

2',5'-phosphodiesterase 12

2'-phosphodiesterase

mitochondrial deadenylase

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pde12 NCBI NCBI:201626