2. Gene
  3. Prdm9 - PR domain containing 9 Gene

Prdm9 - PR domain containing 9 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Rcr1; Dsbc1; repro7; Meisetz; PRDM9-B; G1-419-29

基因 ID: 213389 | 基因类型: protein coding

关于 Prdm9

功能概要

Enables DNA binding activity; histone-lysine N-methyltransferase activity; and protein homodimerization activity. Involved in several processes, including gamete generation; histone lysine methylation; and meiosis I. Acts upstream of or within several processes, including histone methylation; positive regulation of meiotic nuclear division; and positive regulation of transcription by RNA polymerase II. Located in chromatin and nucleus. Is expressed in embryo and head. Orthologous to human PRDM9 (PR/SET domain 9). [provided by Alliance of Genome Resources, Apr 2022]

Prdm9 基因产物(2)

mRNA Protein Name
NM_001361436.1 NP_001348365.1 histone-lysine N-methyltransferase PRDM9 isoform 2
NM_144809.3 NP_659058.3 histone-lysine N-methyltransferase PRDM9 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables histone H3K36 methyltransferase activity IMP
IMP: 通过突变表型推断
27362481 MGI
enables histone H3K4 methyltransferase activity EXP
EXP: 通过实验结果推断
16292313 MGI
enables histone H3K4 methyltransferase activity IDA
IDA: 通过直接分析推断
16292313 MGI
enables histone H3K4 methyltransferase activity IMP
IMP: 通过突变表型推断
16292313 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
27932493 MGI
enables protein homodimerization activity IDA
IDA: 通过直接分析推断
24095733 MGI
enables recombination hotspot binding IDA
IDA: 通过直接分析推断
22028627 MGI
enables recombination hotspot binding IMP
IMP: 通过突变表型推断
24151354 MGI
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
22028627 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in double-strand break repair involved in meiotic recombination IMP
IMP: 通过突变表型推断
25894966 MGI
involved in female gamete generation IMP
IMP: 通过突变表型推断
29478809 MGI
involved in homologous chromosome pairing at meiosis IMP
IMP: 通过突变表型推断
25894966 MGI
involved in male gamete generation IMP
IMP: 通过突变表型推断
29478809 MGI
acts upstream of meiosis I IMP
IMP: 通过突变表型推断
16292313 MGI
involved in negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
27932493 MGI
involved in positive regulation of fertilization IMP
IMP: 通过突变表型推断
25894966 MGI
acts upstream of or within positive regulation of meiosis I IMP
IMP: 通过突变表型推断
16292313 MGI
acts upstream of or within positive regulation of reciprocal meiotic recombination IMP
IMP: 通过突变表型推断
20044538 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
16292313 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
16292313 MGI
acts upstream of or within spermatogenesis IMP
IMP: 通过突变表型推断
19074312 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in chromatin IDA
IDA: 通过直接分析推断
29478809 MGI
located in nucleus IDA
IDA: 通过直接分析推断
25894966 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

histone-lysine N-methyltransferase PRDM9

PR domain zinc finger protein 9

PR domain-containing protein 9

VPR domain containing 9

[histone H3]-lysine36 N-trimethyltransferase PRDM9

[histone H3]-lysine4 N-trimethyltransferase PRDM9

[histone H3]-lysine9 N-trimethyltransferase PRDM9

[histone H4

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-114209 MRK-740 Inhibitor 99.84% 否
HY-RS11073 PRDM9 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-176820 MRK-740-NC Inhibitor / 否
HY-RS19230 Prdm9 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25719 Prdm9 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Prdm9 NCBI NCBI:56979
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z