1. Gene
  2. Tcf7 - transcription factor 7, T cell specific Gene

Tcf7 - transcription factor 7, T cell specific Gene

种属: Mus musculus

同用名: Tcf1; TCF-1

基因 ID: 21414 | 基因类型: protein coding

关于 Tcf7

功能概要

This gene encodes a transcription factor which is a member of the T-cell specific transcription factor family. The encoded protein is distinct from the hepatic transcription factor, transcription factor 1, which is also referred to by the symbol Tcf1. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Sep 2015]

Tcf7 基因产物(2)

mRNA Protein Name
NM_001313981.1 NP_001300910.1 transcription factor 7
NM_009331.4 NP_033357.1 transcription factor 7
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
1827138 MGI
enables DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
12235125 MGI
enables DNA-binding transcription repressor activity IMP
IMP: 通过突变表型推断
17218525 MGI
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IMP
IMP: 通过突变表型推断
22723415 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
22723415 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
17218525 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within T cell receptor V(D)J recombination IGI
IGI: 通过遗传相互作用推断
9462507 MGI
acts upstream of or within alpha-beta T cell differentiation IGI
IGI: 通过遗传相互作用推断
9462507 MGI
involved in canonical Wnt signaling pathway IDA
IDA: 通过直接分析推断
12235125 MGI
involved in canonical Wnt signaling pathway involved in negative regulation of apoptotic process IDA
IDA: 通过直接分析推断
12235125 MGI
acts upstream of or within embryonic digestive tract morphogenesis IGI
IGI: 通过遗传相互作用推断
15057272 MGI
acts upstream of or within embryonic genitalia morphogenesis IGI
IGI: 通过遗传相互作用推断
15057272 MGI
acts upstream of or within embryonic hindgut morphogenesis IGI
IGI: 通过遗传相互作用推断
15057272 MGI
involved in gamma-delta T cell differentiation IMP
IMP: 通过突变表型推断
30413363 MGI
involved in negative regulation of apoptotic process IDA
IDA: 通过直接分析推断
12235125 MGI
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
22723415 MGI
acts upstream of or within neural tube development IGI
IGI: 通过遗传相互作用推断
15057272 MGI
involved in regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
23562159 MGI
acts upstream of or within regulation of cell population proliferation IDA
IDA: 通过直接分析推断
12235125 MGI
involved in regulation of gamma-delta T cell differentiation IMP
IMP: 通过突变表型推断
23562159 MGI
acts upstream of or within regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
12235125 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in euchromatin IDA
IDA: 通过直接分析推断
22723415 MGI
located in nucleus IDA
IDA: 通过直接分析推断
1827138 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

transcription factor 7

T-cell-specific transcription factor 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tcf7 NCBI NCBI:6932