2. Gene
  3. Timp3 - tissue inhibitor of metalloproteinase 3 Gene

Timp3 - tissue inhibitor of metalloproteinase 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Timp-3

基因 ID: 21859 | 基因类型: protein coding

关于 Timp3

功能概要

Predicted to enable metalloendopeptidase inhibitor activity and protease binding activity. Involved in negative regulation of metalloendopeptidase activity. Acts upstream of or within cellular response to organic substance. Located in basement membrane. Is expressed in several structures, including alimentary system; central nervous system; eye posterior segment; genitourinary system; and musculoskeletal system. Used to study Sorsby's fundus dystrophy and dilated cardiomyopathy. Human ortholog(s) of this gene implicated in Sorsby's fundus dystrophy; breast carcinoma; and urinary bladder Cancer. Orthologous to human TIMP3 (TIMP metallopeptidase inhibitor 3). [provided by Alliance of Genome Resources, Apr 2022]

Timp3 基因产物(1)

mRNA Protein Name
NM_011595.2 NP_035725.1 metalloproteinase inhibitor 3 precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of metalloendopeptidase activity IMP
IMP: 通过突变表型推断
24812324 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in basement membrane IDA
IDA: 通过直接分析推断
12950084 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

metalloproteinase inhibitor 3

tissue inhibitor of metalloproteinases 3

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-145426 MPT0B390 Inhibitor 98.76% 否
HY-RS14540 TIMP3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18302 Timp3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24780 Timp3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Timp3 NCBI NCBI:7078
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