1. Gene
  2. Tle2 - transducin-like enhancer of split 2 Gene

Tle2 - transducin-like enhancer of split 2 Gene

种属: Mus musculus

同用名: Grg2; mKIAA4188

基因 ID: 21886 | 基因类型: protein coding

关于 Tle2

功能概要

Predicted to enable transcription corepressor activity. Predicted to be involved in negative regulation of canonical Wnt signaling pathway and negative regulation of transcription, DNA-templated. Predicted to act upstream of or within Wnt signaling pathway. Predicted to be located in focal adhesion and nuclear body. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; central nervous system; integumental system; limb; and sensory organ. Orthologous to human TLE2 (TLE family member 2, transcriptional corepressor). [provided by Alliance of Genome Resources, Apr 2022]

Tle2 基因产物(2)

mRNA Protein Name
NM_001252401.1 NP_001239330.1 transducin-like enhancer protein 2 isoform 2
NM_019725.2 NP_062699.1 transducin-like enhancer protein 2 isoform 1
蛋白主名 其他名称

transducin-like enhancer protein 2

groucho-related protein

transducin-like enhancer of split 2, homolog of Drosophila E(spl)

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tle2 NCBI NCBI:7089