2. Gene
  3. Tle3 - transducin-like enhancer of split 3 Gene

Tle3 - transducin-like enhancer of split 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: ESG; Grg3a; Grg3b; mKIAA1547; 2610103N05Rik

基因 ID: 21887 | 基因类型: protein coding

关于 Tle3

功能概要

Predicted to enable transcription corepressor activity. Involved in negative regulation of cold-induced thermogenesis. Predicted to be located in nucleoplasm. Predicted to be part of beta-catenin-TCF complex. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and sensory organ. Orthologous to human TLE3 (TLE family member 3, transcriptional corepressor). [provided by Alliance of Genome Resources, Apr 2022]

Tle3 基因产物(3)

mRNA Protein Name
NM_001083927.1 NP_001077396.1 transducin-like enhancer protein 3 isoform 1
NM_001083928.1 NP_001077397.1 transducin-like enhancer protein 3 isoform 3
NM_009389.2 NP_033415.2 transducin-like enhancer protein 3 isoform 2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
17202186 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of cold-induced thermogenesis IMP
IMP: 通过突变表型推断
23473036 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

transducin-like enhancer protein 3

grg-3

transducin-like enhancer of split 3, homolog of Drosophila E(spl)

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14565 TLE3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19963 Tle3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26465 Tle3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tle3 NCBI NCBI:7090
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