1. Gene
  2. Unc119 - unc-119 lipid binding chaperone Gene

Unc119 - unc-119 lipid binding chaperone Gene

种属: Mus musculus

同用名: Rg4; HRG4; MRG4; Rtg4; Unc119h; D11Bhm52

基因 ID: 22248 | 基因类型: protein coding

关于 Unc119

功能概要

The protein encoded by this gene is multifunctional, affecting trafficking of transducin in rod photoreceptors, interacting with src-type tyrosine kinases through SH2 and SH3 interacting domains, and aiding the uptake of bacteria through endocytosis. In addition, the encoded protein acts as a lipid-binding chaperone to help localize some myristoylated proteins correctly. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]

Unc119 基因产物(10)

mRNA Protein Name
NM_001313985.1 NP_001300914.1 protein unc-119 homolog A isoform 1
NM_001313986.1 NP_001300915.1 protein unc-119 homolog A isoform 3
NM_001313987.1 NP_001300916.1 protein unc-119 homolog A isoform 4
NM_001313988.1 NP_001300917.1 protein unc-119 homolog A isoform 5
NM_011676.3 NP_035806.1 protein unc-119 homolog A isoform 2
NM_001313985.1 NP_001300914.1 protein unc-119 homolog A isoform 1
NM_001313986.1 NP_001300915.1 protein unc-119 homolog A isoform 3
NM_001313987.1 NP_001300916.1 protein unc-119 homolog A isoform 4
NM_001313988.1 NP_001300917.1 protein unc-119 homolog A isoform 5
NM_011676.3 NP_035806.1 protein unc-119 homolog A isoform 2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
19781630 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in lipoprotein transport IMP
IMP: 通过突变表型推断
21642972 MGI
involved in negative regulation of caveolin-mediated endocytosis IMP
IMP: 通过突变表型推断
19781630 MGI
involved in negative regulation of clathrin-dependent endocytosis IMP
IMP: 通过突变表型推断
19781630 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

protein unc-119 homolog A

retinal gene 4

retinal protein 4

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Unc119 NCBI NCBI:9094