2. Gene
  3. Vamp2 - vesicle-associated membrane protein 2 Gene

Vamp2 - vesicle-associated membrane protein 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Syb2; Syb-2; sybII; Vamp-2

基因 ID: 22318 | 基因类型: protein coding

关于 Vamp2

功能概要

Enables Calmodulin binding activity; phospholipid binding activity; and syntaxin-1 binding activity. Involved in secretion by cell and synaptic vesicle endocytosis. Acts upstream of or within several processes, including Golgi to plasma membrane protein transport; cellular response to Insulin stimulus; and long-term synaptic potentiation. Located in several cellular components, including secretory vesicle; storage vacuole; and trans-Golgi network. Part of synaptobrevin 2-SNAP-25-syntaxin-1a complex. Is expressed in several structures, including alimentary system; integumental system; nervous system; respiratory system; and sensory organ. Orthologous to human VAMP2 (vesicle associated membrane protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Vamp2 基因产物(1)

mRNA Protein Name
NM_009497.3 NP_033523.1 vesicle-associated membrane protein 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables SNARE binding IDA
IDA: 通过直接分析推断
12145198 MGI
enables calmodulin binding IDA
IDA: 通过直接分析推断
12145198 MGI
enables phospholipid binding IDA
IDA: 通过直接分析推断
12145198 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
10394363 MGI
enables syntaxin binding IPI
IPI: 通过物理相互作用推断
17548353 MGI
enables syntaxin-1 binding IDA
IDA: 通过直接分析推断
18703708 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within Golgi to plasma membrane protein transport IMP
IMP: 通过突变表型推断
20582536 MGI
acts upstream of or within calcium-ion regulated exocytosis IDA
IDA: 通过直接分析推断
12145198 MGI
acts upstream of or within calcium-ion regulated exocytosis IMP
IMP: 通过突变表型推断
15920476 MGI
acts upstream of or within cellular response to insulin stimulus IDA
IDA: 通过直接分析推断
18227281 MGI
acts upstream of or within establishment of localization in cell IMP
IMP: 通过突变表型推断
15920476 MGI
involved in exocytic insertion of neurotransmitter receptor to postsynaptic membrane IDA
IDA: 通过直接分析推断
23395379 MGI
involved in exocytic insertion of neurotransmitter receptor to postsynaptic membrane IMP
IMP: 通过突变表型推断
23395379 MGI
involved in hormone secretion IDA
IDA: 通过直接分析推断
24356748 MGI
acts upstream of or within long-term synaptic potentiation IMP
IMP: 通过突变表型推断
23395379 MGI
acts upstream of or within membrane fusion IMP
IMP: 通过突变表型推断
15920476 MGI
acts upstream of or within positive regulation of intracellular protein transport IMP
IMP: 通过突变表型推断
18227281 MGI
involved in regulated exocytosis IDA
IDA: 通过直接分析推断
24356748 MGI
acts upstream of or within regulation of exocytosis IDA
IDA: 通过直接分析推断
12145198 MGI
acts upstream of or within regulation of vesicle-mediated transport IMP
IMP: 通过突变表型推断
18227281 MGI
involved in synaptic vesicle docking IDA
IDA: 通过直接分析推断
25374362 MGI
involved in synaptic vesicle docking IMP
IMP: 通过突变表型推断
25374362 MGI
involved in synaptic vesicle endocytosis IMP
IMP: 通过突变表型推断
15475946 MGI
acts upstream of or within synaptic vesicle exocytosis IMP
IMP: 通过突变表型推断
11691998 MGI
involved in synaptic vesicle exocytosis IMP
IMP: 通过突变表型推断
15475946 MGI
involved in vesicle-mediated transport in synapse IDA
IDA: 通过直接分析推断
23395379 MGI
involved in vesicle-mediated transport in synapse IMP
IMP: 通过突变表型推断
23395379 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of SNARE complex IDA
IDA: 通过直接分析推断
18535671 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
24356748 MGI
located in cytoplasmic vesicle IDA
IDA: 通过直接分析推断
18505797 MGI
located in cytoplasmic vesicle membrane IDA
IDA: 通过直接分析推断
12490950 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
23395379 MGI
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
23395379 MGI
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
18827011 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
18505797 MGI
located in secretory granule IDA
IDA: 通过直接分析推断
12145198 MGI
located in storage vacuole IDA
IDA: 通过直接分析推断
21828338 MGI
located in synapse IDA
IDA: 通过直接分析推断
18706977 MGI
located in synaptic vesicle IDA
IDA: 通过直接分析推断
15145078 MGI
located in synaptic vesicle membrane IDA
IDA: 通过直接分析推断
12192047 MGI
part of synaptobrevin 2-SNAP-25-syntaxin-1a complex IDA
IDA: 通过直接分析推断
21040848 MGI
located in trans-Golgi network IDA
IDA: 通过直接分析推断
18827011 MGI
located in vesicle IDA
IDA: 通过直接分析推断
17313651 MGI
located in zymogen granule membrane IDA
IDA: 通过直接分析推断
12192047 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

vesicle-associated membrane protein 2

synaptobrevin II

synaptobrevin-2

vesicle-associated membrane 2

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P10809 VAMP Inhibitor 98.13% 否
HY-RS15594 VAMP2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21080 Vamp2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27597 Vamp2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Vamp2 NCBI NCBI:6844
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