2. Gene
  3. Vav2 - vav 2 oncogene Gene

Vav2 - vav 2 oncogene Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Vav-2; 2810040F13Rik

基因 ID: 22325 | 基因类型: protein coding

关于 Vav2

功能概要

This gene encodes a member of the Vav family of Rho guanine nucleotide exchange factors. Vav family proteins are involved in the development and activation of lymphocytes, and the encoded protein may also be involved in angiogenesis. Disruption of this gene in mice is associated with heart, artery, and kidney defects, as well as tachycardia and hypertension. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

Vav2 基因产物(1)

mRNA Protein Name
NM_009500.2 NP_033526.1 guanine nucleotide exchange factor VAV2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables epidermal growth factor receptor binding IPI
IPI: 通过物理相互作用推断
15728722 MGI
enables guanyl-nucleotide exchange factor activity IMP
IMP: 通过突变表型推断
15728722 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
16782872 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cell migration IGI
IGI: 通过遗传相互作用推断
15728722 MGI
acts upstream of or within cell projection assembly IGI
IGI: 通过遗传相互作用推断
15728722 MGI
acts upstream of or within lamellipodium assembly IGI
IGI: 通过遗传相互作用推断
15728722 MGI
acts upstream of or within positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IGI
IGI: 通过遗传相互作用推断
15728722 MGI
acts upstream of or within small GTPase-mediated signal transduction IMP
IMP: 通过突变表型推断
15728722 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
15728722 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
15728722 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

guanine nucleotide exchange factor VAV2

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-12810 EHop-016 Inhibitor 99.38% 否
HY-RS15613 VAV2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22354 Vav2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28876 Vav2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Vav2 NCBI NCBI:7410
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