2. Gene
  3. Was - Wiskott-Aldrich syndrome Gene

Was - Wiskott-Aldrich syndrome Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Wasp

基因 ID: 22376 | 基因类型: protein coding

关于 Was

功能概要

Enables identical protein binding activity. Acts upstream of or within several processes, including actin filament polymerization; cellular response to interferon-gamma; and endosomal transport. Located in cell-cell junction; phagocytic vesicle; and vesicle membrane. Is expressed in brain; heart; liver; and spleen. Used to study IgA glomerulonephritis and Wiskott-Aldrich syndrome. Human ortholog(s) of this gene implicated in Wiskott-Aldrich syndrome; X-linked severe congenital neutropenia; and thrombocytopenia. Orthologous to human WAS (WASP actin nucleation promoting factor). [provided by Alliance of Genome Resources, Apr 2022]

Was 基因产物(1)

mRNA Protein Name
NM_009515.2 NP_033541.1 actin nucleation-promoting factor WAS
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IDA
IDA: 通过直接分析推断
12147689 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
10967094 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within T cell activation IMP
IMP: 通过突变表型推断
11070165 MGI
acts upstream of or within actin filament polymerization IDA
IDA: 通过直接分析推断
12147689 MGI
acts upstream of or within actin filament-based movement IDA
IDA: 通过直接分析推断
12147689 MGI
acts upstream of or within actin polymerization or depolymerization IDA
IDA: 通过直接分析推断
12147689 MGI
acts upstream of or within cellular response to type II interferon IDA
IDA: 通过直接分析推断
19144319 MGI
acts upstream of or within endosomal transport IDA
IDA: 通过直接分析推断
12147689 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell-cell junction IDA
IDA: 通过直接分析推断
23793062 MGI
located in phagocytic vesicle IDA
IDA: 通过直接分析推断
19144319 MGI
located in vesicle membrane IDA
IDA: 通过直接分析推断
12147689 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

actin nucleation-promoting factor WAS

Wiskott-Aldrich syndrome homolog

wiskott-Aldrich syndrome protein homolog

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-158239 MS181 Inhibitor 98.36% 否
HY-RS15741 WAS Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19871 Was Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26370 Was Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Was NCBI NCBI:7454
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