2. Gene
  3. Kdm2a - lysine (K)-specific demethylase 2A Gene

Kdm2a - lysine (K)-specific demethylase 2A Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Fbl7; Cxxc8; Fbl11; Jhdm1; Fbxl11; Gm4560; Jhdm1a; lalina; 100043628; 5530401A10Rik

基因 ID: 225876 | 基因类型: protein coding

关于 Kdm2a

功能概要

Enables unmethylated CpG binding activity. Acts upstream of or within several processes, including chordate embryonic development; heart looping; and positive regulation of macromolecule metabolic process. Located in chromatin. Is expressed in embryo; forebrain; and limb. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human KDM2A (lysine demethylase 2A). [provided by Alliance of Genome Resources, Apr 2022]

Kdm2a 基因产物(1)

mRNA Protein Name
NM_001001984.2 NP_001001984.2 lysine-specific demethylase 2A
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables unmethylated CpG binding IDA
IDA: 通过直接分析推断
20417597 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within heart looping IMP
IMP: 通过突变表型推断
25463925 MGI
acts upstream of or within in utero embryonic development IMP
IMP: 通过突变表型推断
25463925 MGI
acts upstream of or within multicellular organism growth IMP
IMP: 通过突变表型推断
25463925 MGI
acts upstream of or within negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
25463925 MGI
acts upstream of or within negative regulation of gene expression IMP
IMP: 通过突变表型推断
25463925 MGI
acts upstream of or within neural tube closure IMP
IMP: 通过突变表型推断
25463925 MGI
acts upstream of or within neuroepithelial cell differentiation IMP
IMP: 通过突变表型推断
25463925 MGI
acts upstream of or within neuron differentiation IMP
IMP: 通过突变表型推断
25463925 MGI
acts upstream of or within positive regulation of gene expression IMP
IMP: 通过突变表型推断
25463925 MGI
involved in transcription initiation-coupled chromatin remodeling IMP
IMP: 通过突变表型推断
32584788 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in chromatin IDA
IDA: 通过直接分析推断
20417597 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

lysine-specific demethylase 2A

F-box and leucine-rich repeat protein 11

F-box protein containing leucine repeats

F-box/LRR-repeat protein 11

[Histone-H3]-lysine-36 demethylase 1A

jmjC domain-containing histone demethylation protein 1A

相关产品

Pre-clinical Phase
生物活性分子 (8)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-12304 IOX1 Inhibitor 99.89% 否
HY-13643 Daminozide Inhibitor 99.79% 否
HY-107573 KDM2/7-IN-1 Inhibitor 99.9% 否
HY-108706 KDM2A/7A-IN-1 Inhibitor 99.94% 否
HY-RS07209 KDM2A Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16796 Kdm2a Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17111 Kdm3a Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23237 Kdm2a Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Kdm2a NCBI NCBI:22992
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