2. Gene
  3. Piezo1 - piezo-type mechanosensitive ion channel component 1 Gene

Piezo1 - piezo-type mechanosensitive ion channel component 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Fam38a; mKIAA0233; 9630020g22

基因 ID: 234839 | 基因类型: protein coding

关于 Piezo1

功能概要

Enables identical protein binding activity and mechanosensitive cation channel activity. Involved in positive regulation of myotube differentiation. Acts upstream of or within cation transport; detection of mechanical stimulus; and regulation of membrane potential. Located in plasma membrane. Is expressed in several structures, including hemolymphoid system; liver; and lung. Human ortholog(s) of this gene implicated in dehydrated hereditary stomatocytosis 1 and hereditary lymphedema. Orthologous to human PIEZO1 (piezo type mechanosensitive ion channel component 1). [provided by Alliance of Genome Resources, Apr 2022]

Piezo1 基因产物(2)

mRNA Protein Name
NM_001037298.1 NP_001032375.1 piezo-type mechanosensitive ion channel component 1 isoform 2
NM_001357349.1 NP_001344278.1 piezo-type mechanosensitive ion channel component 1 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
22343900 MGI
enables mechanosensitive monoatomic cation channel activity IMP
IMP: 通过突变表型推断
32142647 MGI
enables mechanosensitive monoatomic ion channel activity IDA
IDA: 通过直接分析推断
20813920 MGI
enables mechanosensitive monoatomic ion channel activity IMP
IMP: 通过突变表型推断
38228630 MGI
enables monoatomic cation channel activity IDA
IDA: 通过直接分析推断
20813920 MGI
enables monoatomic cation channel activity IMP
IMP: 通过突变表型推断
20813920 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
24157948 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within detection of mechanical stimulus IMP
IMP: 通过突变表型推断
20813920 MGI
acts upstream of or within monoatomic cation transport IMP
IMP: 通过突变表型推断
32142647 MGI
involved in monoatomic cation transport IMP
IMP: 通过突变表型推断
20813920 MGI
involved in positive regulation of myotube differentiation IMP
IMP: 通过突变表型推断
29799007 MGI
acts upstream of or within regulation of membrane potential IMP
IMP: 通过突变表型推断
20813920 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cuticular plate IDA
IDA: 通过直接分析推断
38228630 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
20813920 MGI
located in stereocilium IDA
IDA: 通过直接分析推断
38228630 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

piezo-type mechanosensitive ion channel component 1

family with sequence similarity 38, member A

protein PIEZO1

相关产品

Pre-clinical Phase
生物活性分子 (12)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-18723 Yoda 1 99.97% 否
HY-P1410 GsMTx4 Inhibitor 99.83% 否
HY-126010 Dooku1 Antagonist 99.93% 否
HY-P1410A GsMTx4 TFA Inhibitor 99.85% 否
HY-131018 Jedi2 99.93% 否
HY-162501 Yaddle1 Agonist 99.14% 否
HY-175416 Yoda2 99.57% 否
HY-RS10483 PIEZO1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-165607S MCB-22-174 99.78% 否
HY-RS17433 Piezo1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-169332 Piezo1 agonist 1-d2 / 否
HY-RS23888 Piezo1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Piezo1 NCBI NCBI:9780
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