2. Gene
  3. Lrig2 - leucine-rich repeats and immunoglobulin-like domains 2 Gene

Lrig2 - leucine-rich repeats and immunoglobulin-like domains 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: LIG-2; 4632419I10Rik

基因 ID: 269473 | 基因类型: protein coding

关于 Lrig2

功能概要

Enables signaling receptor binding activity. Acts upstream of or within several processes, including negative regulation of axon regeneration; negative regulation of membrane protein ectodomain proteolysis; and positive regulation of protein localization to cell surface. Located in several cellular components, including growth cone; intracellular vesicle; and neuronal cell body. Is expressed in several structures, including branchial arch; central nervous system; eye; inner ear; and nasal pit. Human ortholog(s) of this gene implicated in urofacial syndrome. Orthologous to human LRIG2 (leucine rich repeats and immunoglobulin like domains 2). [provided by Alliance of Genome Resources, Apr 2022]

Lrig2 基因产物(2)

mRNA Protein Name
NM_001025067.2 NP_001020238.1 leucine-rich repeats and immunoglobulin-like domains protein 2 isoform 1 precursor
NM_001310698.1 NP_001297627.1 leucine-rich repeats and immunoglobulin-like domains protein 2 isoform 2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
26651291 MGI
enables signaling receptor binding IPI
IPI: 通过物理相互作用推断
26651291 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within innervation IGI
IGI: 通过遗传相互作用推断
24086156 MGI
acts upstream of membrane protein ectodomain proteolysis IMP
IMP: 通过突变表型推断
26651291 MGI
acts upstream of or within negative regulation of axon regeneration IMP
IMP: 通过突变表型推断
26651291 MGI
acts upstream of or within negative regulation of membrane protein ectodomain proteolysis IMP
IMP: 通过突变表型推断
26651291 MGI
acts upstream of or within negative regulation of neuron projection development IGI
IGI: 通过遗传相互作用推断
26651291 MGI
acts upstream of or within positive regulation of protein localization to cell surface IMP
IMP: 通过突变表型推断
26651291 MGI
acts upstream of protein localization to cell surface IMP
IMP: 通过突变表型推断
26651291 MGI
acts upstream of or within regulation of axon regeneration IGI
IGI: 通过遗传相互作用推断
26651291 MGI
acts upstream of or within regulation of neuron migration IGI
IGI: 通过遗传相互作用推断
26651291 MGI
acts upstream of or within regulation of platelet-derived growth factor receptor signaling pathway IGI
IGI: 通过遗传相互作用推断
24023893 MGI
acts upstream of or within sensory perception of sound IMP
IMP: 通过突变表型推断
24086156 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in growth cone IDA
IDA: 通过直接分析推断
26651291 MGI
located in intracellular vesicle IDA
IDA: 通过直接分析推断
26651291 MGI
located in membrane IDA
IDA: 通过直接分析推断
26651291 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

leucine-rich repeats and immunoglobulin-like domains protein 2

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07788 LRIG2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20982 Lrig2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27499 Lrig2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lrig2 NCBI NCBI:9860
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