2. Gene
  3. Mthfd1l - methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like Gene

Mthfd1l - methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Fthfsdc1; 2410004L15Rik

基因 ID: 270685 | 基因类型: protein coding

关于 Mthfd1l

功能概要

Predicted to enable ATP binding activity; formate-tetrahydrofolate Ligase activity; and protein homodimerization activity. Involved in embryonic neurocranium morphogenesis; embryonic viscerocranium morphogenesis; and neural tube closure. Located in mitochondrion. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Used to study neural tube defect. Human ortholog(s) of this gene implicated in neural tube defect. Orthologous to human MTHFD1L (methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like). [provided by Alliance of Genome Resources, Apr 2022]

Mthfd1l 基因产物(3)

mRNA Protein Name
NM_001170785.1 NP_001164256.1 monofunctional C1-tetrahydrofolate synthase, mitochondrial precursor
NM_001170786.1 NP_001164257.1 monofunctional C1-tetrahydrofolate synthase, mitochondrial precursor
NM_172308.4 NP_758512.3 monofunctional C1-tetrahydrofolate synthase, mitochondrial precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in embryonic neurocranium morphogenesis IMP
IMP: 通过突变表型推断
23267094 MGI
involved in embryonic viscerocranium morphogenesis IMP
IMP: 通过突变表型推断
23267094 MGI
involved in neural tube closure IMP
IMP: 通过突变表型推断
23267094 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrion IDA
IDA: 通过直接分析推断
19948730 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

monofunctional C1-tetrahydrofolate synthase, mitochondrial

formyltetrahydrofolate synthetase domain containing 1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08775 MTHFD1L Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20214 Mthfd1l Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26720 Mthfd1l Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mthfd1l NCBI NCBI:25902
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