2. Gene
  3. Cfb - complement factor B Gene

Cfb - complement factor B Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Bf; Da1-24

基因 ID: 294257 | 基因类型: protein coding

关于 Cfb

功能概要

Predicted to enable G protein-coupled receptor activity and serine-type endopeptidase activity. Involved in complement activation; response to lipopolysaccharide; and response to thyroid hormone. Located in extracellular space. Biomarker of polycystic kidney disease and retinal degeneration. Human ortholog(s) of this gene implicated in several diseases, including atypical hemolytic-uremic syndrome; autoimmune disease (multiple); eye disease (multiple); glomerulonephritis (multiple); and sickle cell anemia. Orthologous to human CFB (Complement Factor B). [provided by Alliance of Genome Resources, Apr 2022]

Cfb 基因产物(1)

mRNA Protein Name
NM_212466.3 NP_997631.2 complement factor B precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in complement activation IDA
IDA: 通过直接分析推断
6906329 RGD
involved in response to lipopolysaccharide IEP
IEP: 通过表达模式推断
18023983 RGD
involved in response to thyroid hormone IMP
IMP: 通过突变表型推断
22370704 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
3853462 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

complement factor B

B-factor, properdin

properdin factor B

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-148370A Sefaxersen sodium Inhibitor / Phase 2
Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-148370 Sefaxersen Inhibitor / 否
HY-174913 Factor B-IN-5 Inhibitor / 否
HY-RS02557 CFB Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17438 Cfb Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23894 Cfb Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cfb NCBI NCBI:629
Mus musculus Cfb NCBI NCBI:14962
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z