2. Gene
  3. Setd2 - SET domain containing 2, histone lysine methyltransferase Gene

Setd2 - SET domain containing 2, histone lysine methyltransferase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 316013 | 基因类型: protein coding

关于 Setd2

功能概要

Predicted to enable alpha-tubulin binding activity and Histone Methyltransferase activity (H3-K36 specific). Predicted to be involved in several processes, including defense response to Other organism; nucleic acid metabolic process; and peptidyl-lysine methylation. Predicted to act upstream of or within several processes, including animal organ development; histone H3-K36 trimethylation; and tube morphogenesis. Predicted to be located in chromosome and nucleus. Human ortholog(s) of this gene implicated in carcinoma (multiple); gastrointestinal system Cancer (multiple); idiopathic pulmonary fibrosis; and malignant mesothelioma. Orthologous to human SETD2 (SET domain containing 2, histone lysine methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Setd2 基因产物(1)

mRNA Protein Name
NM_001401163.1 NP_001388092.1 histone-lysine N-methyltransferase SETD2
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of ossification IMP
IMP: 通过突变表型推断
30746871 RGD
involved in response to alkaloid IEP
IEP: 通过表达模式推断
27846294 RGD
involved in response to metal ion IEP
IEP: 通过表达模式推断
30746871 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
27766425 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

histone-lysine N-methyltransferase SETD2

相关产品

Clinical Phase
生物活性分子 (2)
目录号 产品名 作用方式
纯度 Phase
HY-136328 EZM0414 TFA Inhibitor 97.20% Phase 1
HY-144858 EZM0414 Inhibitor 99.11% Phase 1
Pre-clinical Phase
生物活性分子 (8)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-139626 EPZ-719 Inhibitor 99.00% 否
HY-173156 UNC10013 Modulator 99.90% 否
HY-P10463A ssK36 TFA Inhibitor 99.34% 否
HY-RS12742 SETD2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-124699 MMSET-IN-1 Inhibitor / 否
HY-P10463 ssK36 Inhibitor / 否
HY-RS16976 Setd2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23419 Setd2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Setd2 NCBI NCBI:29072
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