1. Gene
  2. MAP2K7 - Map2k7 mitogen activated protein kinase kinase 7 Gene

MAP2K7 - Map2k7 mitogen activated protein kinase kinase 7 Gene

种属: Rattus norvegicus

同用名: JNKK; Mek7; Mkk7; Jnkk2; Mapkk7

基因 ID: 363855 | 基因类型: protein coding

关于 MAP2K7

功能概要

Enables several functions, including ATP binding activity; JUN kinase kinase activity; and magnesium ion binding activity. Involved in several processes, including JNK cascade; cellular response to sorbitol; and positive regulation of JNK cascade. Located in cytosol and nucleus. Orthologous to human MAP2K7 (mitogen-activated protein kinase kinase 7). [provided by Alliance of Genome Resources, Apr 2022]

MAP2K7 基因产物(2)

mRNA Protein Name
NM_001025425.2 NP_001020596.1 dual specificity mitogen-activated protein kinase kinase 7 isoform 1
NM_001401207.1 NP_001388136.1 dual specificity mitogen-activated protein kinase kinase 7 isoform 2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ATP binding IDA
IDA: 通过直接分析推断
10051439 RGD
enables JUN kinase kinase activity IDA
IDA: 通过直接分析推断
10051439 RGD
enables MAP kinase kinase activity IDA
IDA: 通过直接分析推断
10051439 RGD
enables magnesium ion binding IDA
IDA: 通过直接分析推断
10051439 RGD
enables mitogen-activated protein kinase kinase kinase binding IPI
IPI: 通过物理相互作用推断
14575811 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
15816852 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in JNK cascade IDA
IDA: 通过直接分析推断
10051439 RGD
involved in cellular response to osmotic stress IDA
IDA: 通过直接分析推断
10051439 RGD
involved in cellular response to sorbitol IEP
IEP: 通过表达模式推断
20550965 RGD
involved in positive regulation of JNK cascade IDA
IDA: 通过直接分析推断
10051439 RGD
involved in positive regulation of neuron apoptotic process IMP
IMP: 通过突变表型推断
12514131 RGD
involved in positive regulation of protein phosphorylation IDA
IDA: 通过直接分析推断
20550965 RGD
involved in protein phosphorylation IDA
IDA: 通过直接分析推断
10051439 RGD
involved in response to osmotic stress IDA
IDA: 通过直接分析推断
10051439 RGD
involved in stress-activated MAPK cascade IDA
IDA: 通过直接分析推断
10051439 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

dual specificity mitogen-activated protein kinase kinase 7

JNK kinase 2

JNK-activating kinase 2

JNKK 2

MAP kinase kinase 7

MAPK/ERK kinase 7

MAPKK 7

MEK 7

c-Jun N-terminal kinase kinase 2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens MAP2K7 NCBI NCBI:5609