1. Gene
  2. Fbxo7 - F-box protein 7 Gene

Fbxo7 - F-box protein 7 Gene

种属: Rattus norvegicus

基因 ID: 366854 | 基因类型: protein coding

关于 Fbxo7

功能概要

Predicted to enable several functions, including enzyme binding activity; protein heterodimerization activity; and ubiquitin ligase-substrate adaptor activity. Involved in negative regulation of neuron death and positive regulation of Autophagy of mitochondrion. Predicted to be located in several cellular components, including Lewy body core; Lewy body corona; and Lewy neurite. Predicted to be part of SCF ubiquitin Ligase complex. Human ortholog(s) of this gene implicated in Parkinson's disease and Parkinson's disease 15. Orthologous to human FBXO7 (F-box protein 7). [provided by Alliance of Genome Resources, Apr 2022]

Fbxo7 基因产物(1)

mRNA Protein Name
NM_001012222.1 NP_001012222.1 F-box only protein 7
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of negative regulation of neuron apoptotic process IMP
IMP: 通过突变表型推断
26310625 RGD
involved in positive regulation of mitophagy IMP
IMP: 通过突变表型推断
26310625 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

F-box only protein 7

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fbxo7 NCBI NCBI:25793