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  2. HECA - hdc homolog, cell cycle regulator Gene

HECA - hdc homolog, cell cycle regulator Gene

中文名称:hdc 同源物,细胞周期调节因子

种属: Homo sapiens

同用名: HDC; HDCL; HHDC; dJ225E12.1

基因 ID: 51696 | 基因类型: protein coding

关于 HECA

Cytogenetic location: 6q24.1 Genomic coordinates (GRCh38): 6:139,135,080-139,180,802 (from NCBI)

This gene has 1 transcript (splice variant) and 205 orthologues. Ubiquitous expression in lymph node (RPKM 16.9), spleen (RPKM 16.5) and 25 other tissues.

功能概要

该基因编码果蝇头壳蛋白的同系物,这是一种高度碱性的细胞质蛋白,在成体形态发生过程中调节成虫细胞重新进入有丝分裂周期。在果蝇中,编码的蛋白质还在气管发育过程中抑制邻近细胞的末端分支。[RefSeq 提供,2008 年 7 月]

This gene encodes the homolog of the Drosophila headcase protein, a highly basic, cytoplasmic protein that regulates the re-entry of imaginal cells into the mitotic cycle during adult morphogenesis. In Drosophila, the encoded protein also inhibits terminal branching of neighboring cells during tracheal development. [provided by RefSeq, Jul 2008]

HECA 基因产物(1)

mRNA Protein Name
NM_016217.3 NP_057301.1 headcase protein homolog
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of mitotic cell cycle IDA
IDA: 通过直接分析推断
19643820 GOA
involved in negative regulation of mitotic cell cycle IMP
IMP: 通过突变表型推断
22100912 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
19643820 GOA
located in nucleus IDA
IDA: 通过直接分析推断
19643820 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

HECA 蛋白结构

HECA

HECA: Headcase protein family homologue (94 - 191)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 543 a.a.
蛋白主名 其他名称

headcase protein homolog

headcase homolog

关联疾病

疾病名称 别名
Lichen Nitidus

Pinkus' Disease

Venous Hemangioma
Parapsoriasis

Digitate Dermatosis

Parapsoriasis En Plaque

Parapsoriasis En Plaques

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Felis catus HECA VGNC VGNC:102438
Macaca mulatta HECA VGNC VGNC:73207
Mus musculus HECA MGD MGI:2685715
Rattus norvegicus HECA RGD RGD:1304818
Bos taurus HECA VGNC VGNC:29799
Canis familiaris HECA VGNC VGNC:41641