2. Gene
  3. Irf7 - interferon regulatory factor 7 Gene

Irf7 - interferon regulatory factor 7 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

基因 ID: 54123 | 基因类型: protein coding

关于 Irf7

功能概要

Enables DNA-binding transcription factor activity, RNA polymerase II-specific and cis-regulatory region sequence-specific DNA binding activity. Involved in defense response to Other organism; positive regulation of transcription, DNA-templated; and regulation of Toll-like Receptor signaling pathway. Acts upstream of or within immunoglobulin mediated immune response; positive regulation of type I interferon production; and positive regulation of type I interferon-mediated signaling pathway. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Is expressed in apical ectodermal ridge; embryo; liver; and ureter. Human ortholog(s) of this gene implicated in immunodeficiency 39. Orthologous to human IRF7 (interferon regulatory factor 7). [provided by Alliance of Genome Resources, Apr 2022]

Irf7 基因产物(3)

mRNA Protein Name
NM_001252600.1 NP_001239529.1 interferon regulatory factor 7 isoform 2
NM_001252601.1 NP_001239530.1 interferon regulatory factor 7 isoform 3
NM_016850.3 NP_058546.1 interferon regulatory factor 7 isoform 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription factor activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
22095711 MGI
enables DNA-binding transcription factor activity, RNA polymerase II-specific IMP
IMP: 通过突变表型推断
27129230 MGI
enables cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
27129230 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
16236719 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in defense response to virus IMP
IMP: 通过突变表型推断
27129230 MGI
acts upstream of or within immunoglobulin mediated immune response IMP
IMP: 通过突变表型推断
15800576 MGI
involved in positive regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
27129230 MGI
involved in positive regulation of type I interferon production IDA
IDA: 通过直接分析推断
22095711 MGI
acts upstream of or within positive regulation of type I interferon production IGI
IGI: 通过遗传相互作用推断
23956435 MGI
acts upstream of or within positive regulation of type I interferon-mediated signaling pathway IMP
IMP: 通过突变表型推断
17618271 MGI
involved in regulation of MyD88-dependent toll-like receptor signaling pathway IMP
IMP: 通过突变表型推断
15800576 MGI
involved in regulation of MyD88-independent toll-like receptor signaling pathway IMP
IMP: 通过突变表型推断
15800576 MGI
acts upstream of or within regulation of gene expression IGI
IGI: 通过遗传相互作用推断
23160154 MGI
acts upstream of or within type I interferon production IMP
IMP: 通过突变表型推断
15800576 MGI
involved in type I interferon-mediated signaling pathway IMP
IMP: 通过突变表型推断
27129230 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

interferon regulatory factor 7

IRF-7

相关产品

Clinical Phase
生物活性分子 (2)
目录号 产品名 作用方式
纯度 Phase
HY-176426 Subquinocin 99.83% Phase 4
HY-146244 Agatolimod 98.84% Phase 3
Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-117066 CL075 Agonist 99.18% 否
HY-122891 SB02024 99.70% 否
HY-RS06911 IRF7 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16952 Irf7 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-178690 MyD88-IN-4 Inhibitor / 否
HY-174663 Human IFNE mRNA / 否
HY-RS23395 Irf7 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Irf7 NCBI NCBI:3665
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