2. Gene
  3. Nr4a2 - nuclear receptor subfamily 4, group A, member 2 Gene

Nr4a2 - nuclear receptor subfamily 4, group A, member 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: RNR1; Nurr1

基因 ID: 54278 | 基因类型: protein coding

关于 Nr4a2

功能概要

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including animal organ development; negative regulation of neuron apoptotic process; and positive regulation of transcription by RNA polymerase II. Acts upstream of or within response to inorganic substance and response to Insecticide. Located in chromatin; cytoplasm; and nucleus. Biomarker of Parkinsonism and epilepsy. Human ortholog(s) of this gene implicated in Parkinson's disease. Orthologous to human NR4A2 (nuclear receptor subfamily 4 group A member 2). [provided by Alliance of Genome Resources, Apr 2022]

Nr4a2 基因产物(1)

mRNA Protein Name
NM_019328.3 NP_062201.2 nuclear receptor subfamily 4 group A member 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
8737662 RGD
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
8737662 RGD
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
8737662 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cerebral cortex development IEP
IEP: 通过表达模式推断
21056632 RGD
involved in learning or memory IMP
IMP: 通过突变表型推断
17142303 RGD
involved in negative regulation of neuron apoptotic process IMP
IMP: 通过突变表型推断
22294685 RGD
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
8737662 RGD
acts upstream of or within response to insecticide IDA
IDA: 通过直接分析推断
8737662 RGD
involved in retina development in camera-type eye IEP
IEP: 通过表达模式推断
22714110 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in chromatin IDA
IDA: 通过直接分析推断
28743636 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

nuclear receptor subfamily 4 group A member 2

NUR-related factor 1

RNR-1

SL-322

nuclear orphan receptor HZF-3

nuclear receptor subfamily 4 group A member 2 variant NURR1a

nuclear receptor subfamily 4 group A member 2 variant NURR1b

nuclear receptor subfamily 4 group A member 2 variant NURR1c

n

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-174340 Nurr1 agonist 13 Agonist / 否
HY-RS09551 NR4A2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17344 Nr4a2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23798 Nr4a2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nr4a2 NCBI NCBI:4929
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z