2. Gene
  3. Stap1 - signal transducing adaptor family member 1 Gene

Stap1 - signal transducing adaptor family member 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Brdg1; STAP-1

基因 ID: 56792 | 基因类型: protein coding

关于 Stap1

功能概要

Enables macrophage colony-stimulating factor receptor binding activity and transmembrane receptor protein tyrosine kinase adaptor activity. Involved in several processes, including negative regulation of macrophage colony-stimulating factor signaling pathway; negative regulation of macrophage migration; and positive regulation of cellular component organization. Acts upstream of or within response to bacterium and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be located in mitochondrion and nucleoplasm. Predicted to be part of protein-containing complex. Orthologous to human STAP1 (signal transducing adaptor family member 1). [provided by Alliance of Genome Resources, Apr 2022]

Stap1 基因产物(2)

mRNA Protein Name
NM_001310639.1 NP_001297568.1 signal-transducing adaptor protein 1 isoform 2
NM_019992.4 NP_064376.1 signal-transducing adaptor protein 1 isoform 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables macrophage colony-stimulating factor receptor binding IPI
IPI: 通过物理相互作用推断
19100238 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
10679268 MGI
enables protein-macromolecule adaptor activity IDA
IDA: 通过直接分析推断
10679268 MGI
enables receptor tyrosine kinase binding IPI
IPI: 通过物理相互作用推断
19100238 MGI
enables transmembrane receptor protein tyrosine kinase adaptor activity IDA
IDA: 通过直接分析推断
19100238 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cell surface receptor protein tyrosine kinase signaling pathway IDA
IDA: 通过直接分析推断
10679268 MGI
involved in cell surface receptor protein tyrosine kinase signaling pathway IDA
IDA: 通过直接分析推断
19100238 MGI
involved in cellular response to lipopolysaccharide IDA
IDA: 通过直接分析推断
19100238 MGI
involved in negative regulation of macrophage chemotaxis IMP
IMP: 通过突变表型推断
19100238 MGI
involved in negative regulation of macrophage colony-stimulating factor signaling pathway IMP
IMP: 通过突变表型推断
19100238 MGI
involved in negative regulation of microglial cell migration IMP
IMP: 通过突变表型推断
19100238 MGI
involved in negative regulation of phosphorylation IDA
IDA: 通过直接分析推断
19100238 MGI
involved in negative regulation of ruffle assembly IMP
IMP: 通过突变表型推断
19100238 MGI
involved in positive regulation of gene expression IDA
IDA: 通过直接分析推断
19100238 MGI
involved in positive regulation of microglial cell activation IMP
IMP: 通过突变表型推断
19100238 MGI
involved in positive regulation of microglial cell mediated cytotoxicity IDA
IDA: 通过直接分析推断
19100238 MGI
involved in positive regulation of phagocytosis, engulfment IDA
IDA: 通过直接分析推断
19100238 MGI
acts upstream of or within response to bacterium IEP
IEP: 通过表达模式推断
23012479 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

signal-transducing adaptor protein 1

BCR downstream signaling 1

stem cell adaptor protein STAP-1

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13873 STAP1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS15591 UXT Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20497 Stap1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27005 Stap1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Stap1 NCBI NCBI:26228
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