2. Gene
  3. Vav3 - vav 3 oncogene Gene

Vav3 - vav 3 oncogene Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Idd18.1; A530094I06Rik

基因 ID: 57257 | 基因类型: protein coding

关于 Vav3

功能概要

Enables epidermal growth factor receptor binding activity and guanyl-nucleotide exchange factor activity. Acts upstream of or within several processes, including integrin-mediated signaling pathway; neutrophil chemotaxis; and positive regulation of phosphatidylinositol 3-kinase activity. Located in cytoplasm and plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; limb segment; metanephros; and sensory organ. Orthologous to human VAV3 (vav guanine nucleotide exchange factor 3). [provided by Alliance of Genome Resources, Apr 2022]

Vav3 基因产物(3)

mRNA Protein Name
NM_001378987.1 NP_001365916.1 guanine nucleotide exchange factor VAV3 isoform 3
NM_020505.2 NP_065251.2 guanine nucleotide exchange factor VAV3 isoform 1
NM_146139.2 NP_666251.1 guanine nucleotide exchange factor VAV3 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables epidermal growth factor receptor binding IPI
IPI: 通过物理相互作用推断
15728722 MGI
enables guanyl-nucleotide exchange factor activity IGI
IGI: 通过遗传相互作用推断
15249579 MGI
enables guanyl-nucleotide exchange factor activity IMP
IMP: 通过突变表型推断
15728722 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
16782872 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cell migration IGI
IGI: 通过遗传相互作用推断
15728722 MGI
acts upstream of or within cell projection assembly IGI
IGI: 通过遗传相互作用推断
15728722 MGI
acts upstream of or within integrin-mediated signaling pathway IGI
IGI: 通过遗传相互作用推断
15249579 MGI
acts upstream of or within lamellipodium assembly IGI
IGI: 通过遗传相互作用推断
15728722 MGI
acts upstream of or within neutrophil chemotaxis IGI
IGI: 通过遗传相互作用推断
21178006 MGI
acts upstream of or within positive regulation of cell adhesion IGI
IGI: 通过遗传相互作用推断
15249579 MGI
acts upstream of or within positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IGI
IGI: 通过遗传相互作用推断
15728722 MGI
acts upstream of or within regulation of GTPase activity IGI
IGI: 通过遗传相互作用推断
15249579 MGI
acts upstream of or within small GTPase-mediated signal transduction IMP
IMP: 通过突变表型推断
15728722 MGI
acts upstream of or within vesicle fusion IGI
IGI: 通过遗传相互作用推断
15249579 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
15728722 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
15728722 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

guanine nucleotide exchange factor VAV3

VAV-3

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15614 VAV3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20835 Vav3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27349 Vav3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Vav3 NCBI NCBI:10451
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