2. Gene
  3. PDP2 - pyruvate dehydrogenase phosphatase catalytic subunit 2 Gene

PDP2 - pyruvate dehydrogenase phosphatase catalytic subunit 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：丙酮酸脱氢酶磷酸酶催化亚基 2

种属: Homo sapiens

同用名: PPM2B; PDPC 2; PPM2C2

基因 ID: 57546 | 基因类型: protein coding

关于 PDP2

Cytogenetic location: 16q22.1 Genomic coordinates (GRCh38): 16:66,880,515-66,891,101 (from NCBI)

This gene has 9 transcripts (splice variants), 198 orthologues and 16 paralogues. Ubiquitous expression in thyroid (RPKM 4.8), kidney (RPKM 4.0) and 25 other tissues.

功能概要

该基因是一种线粒体蛋白，起磷酸酶的作用，参与丙酮酸脱氢酶复合物的酶促重置。可变剪接导致编码相同蛋白质的多个转录变体。[RefSeq 提供，2016 年 8 月]

This gene is a mitochondrial protein that functions as a Phosphatase and is involved in the enzymatic resetting of the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2016]

PDP2 基因产物(8)

mRNA Protein Name
NM_001329928.2 NP_001316857.1 [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial precursor
NM_001329929.2 NP_001316858.1 [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial precursor
NM_001329930.2 NP_001316859.1 [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial precursor
NM_001329931.2 NP_001316860.1 [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial precursor
NM_001329932.2 NP_001316861.1 [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial precursor
NM_001329933.2 NP_001316862.1 [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial precursor
NM_001329934.2 NP_001316863.1 [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial precursor
NM_020786.4 NP_065837.1 [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial precursor

PDP2 蛋白结构

PP2C

PP2C: Protein phosphatase 2C (227 - 442)

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  • 529 a.a.
蛋白主名 其他名称

[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial

protein phosphatase 2C, magnesium-dependent, catalytic subunit 2

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10286 PDP2 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta PDP2 VGNC VGNC:75896
Bos taurus PDP2 VGNC VGNC:32714
Mus musculus PDP2 MGD MGI:1918878
Felis catus PDP2 VGNC VGNC:64094
Rattus norvegicus PDP2 RGD RGD:628812
Canis familiaris PDP2 VGNC VGNC:44389
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