2. Gene
  3. Cltc - clathrin, heavy polypeptide (Hc) Gene

Cltc - clathrin, heavy polypeptide (Hc) Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: CHC; 3110065L21Rik

基因 ID: 67300 | 基因类型: protein coding

关于 Cltc

功能概要

Enables protein kinase binding activity. Predicted to be involved in several processes, including amyloid-beta clearance by transcytosis; endocytosis; and negative regulation of hyaluronan biosynthetic process. Predicted to act upstream of or within mitotic spindle assembly. Located in clathrin-coated pit and photoreceptor ribbon synapse. Part of membrane coat. Is active in presynaptic endocytic zone membrane. Is expressed in 8-cell stage embryo; brain; placenta; and unsegmented mesenchyme. Human ortholog(s) of this gene implicated in autosomal dominant mental retardation 56. Orthologous to human CLTC (clathrin heavy chain). [provided by Alliance of Genome Resources, Apr 2022]

Cltc 基因产物(2)

mRNA Protein Name
NM_001003908.2 NP_001003908.1 clathrin heavy chain 1 isoform 2
NM_001356393.1 NP_001343322.1 clathrin heavy chain 1 isoform 1
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
23746204 MGI
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
21307259 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in clathrin-coated pit IDA
IDA: 通过直接分析推断
26437238 MGI
is active in glutamatergic synapse EXP
EXP: 通过实验结果推断
17028301 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
17028301 MGI
located in membrane IMP
IMP: 通过突变表型推断
20080761 MGI
part of membrane coat IDA
IDA: 通过直接分析推断
11879655 MGI
is active in photoreceptor ribbon synapse IDA
IDA: 通过直接分析推断
23785143 MGI
is active in postsynaptic endocytic zone EXP
EXP: 通过实验结果推断
17028301 MGI
is active in postsynaptic endocytic zone IDA
IDA: 通过直接分析推断
17028301 MGI
is active in presynaptic endocytic zone membrane IDA
IDA: 通过直接分析推断
23785143 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

clathrin heavy chain 1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02845 CLTC Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21314 Cltc Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27833 Cltc Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cltc NCBI NCBI:1213
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