1. Gene
  2. Phf19 - PHD finger protein 19 Gene

Phf19 - PHD finger protein 19 Gene

种属: Mus musculus

同用名: 3110009G19Rik; 3321402G02Rik

基因 ID: 74016 | 基因类型: protein coding

关于 Phf19

功能概要

Enables methylated histone binding activity. Involved in several processes, including negative regulation of transcription by RNA polymerase II; positive regulation of histone H3-K27 methylation; and stem cell population maintenance. Part of ESC/E(Z) complex. Is expressed in brain ventricular layer; early conceptus; eye; genitourinary system; and intestine. Orthologous to human PHF19 (PHD finger protein 19). [provided by Alliance of Genome Resources, Apr 2022]

Phf19 基因产物(1)

mRNA Protein Name
NM_028716.4 NP_082992.1 PHD finger protein 19
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables methylated histone binding IDA
IDA: 通过直接分析推断
23104054 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in epigenetic regulation of gene expression IMP
IMP: 通过突变表型推断
22438827 MGI
involved in negative regulation of gene expression, epigenetic IMP
IMP: 通过突变表型推断
23104054 MGI
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
23104054 MGI
involved in stem cell differentiation IMP
IMP: 通过突变表型推断
23104054 MGI
involved in stem cell population maintenance IMP
IMP: 通过突变表型推断
22438827 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of ESC/E(Z) complex IDA
IDA: 通过直接分析推断
22438827 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

PHD finger protein 19

polycomb-like protein 3

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Phf19 NCBI NCBI:26147