2. Gene
  3. Errfi1 - ERBB receptor feedback inhibitor 1 Gene

Errfi1 - ERBB receptor feedback inhibitor 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Mig6; RALT; Mig-6; 1300002F13Rik

基因 ID: 74155 | 基因类型: protein coding

关于 Errfi1

功能概要

Predicted to enable SH3 domain binding activity; protein kinase binding activity; and small GTPase binding activity. Involved in several processes, including lung development; negative regulation of epidermal growth factor-activated receptor activity; and skin morphogenesis. Located in cytoplasm. Is extrinsic component of cytoplasmic side of plasma membrane. Is expressed in alveolar system; lung; and lung epithelium. Used to study endometrial Cancer and osteoarthritis. Orthologous to human ERRFI1 (ERBB receptor feedback inhibitor 1). [provided by Alliance of Genome Resources, Apr 2022]

Errfi1 基因产物(2)

mRNA Protein Name
NM_001356323.1 NP_001343252.1 ERBB receptor feedback inhibitor 1
NM_133753.2 NP_598514.1 ERBB receptor feedback inhibitor 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
15102471 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within apoptotic process IDA
IDA: 通过直接分析推断
22975324 MGI
acts upstream of or within apoptotic process IGI
IGI: 通过遗传相互作用推断
20418913 MGI
acts upstream of or within apoptotic process IMP
IMP: 通过突变表型推断
22975324 MGI
acts upstream of or within bile acid biosynthetic process IMP
IMP: 通过突变表型推断
22912762 MGI
acts upstream of or within cartilage development IMP
IMP: 通过突变表型推断
24550287 MGI
acts upstream of or within cell cycle IMP
IMP: 通过突变表型推断
25976672 MGI
acts upstream of or within cell migration IDA
IDA: 通过直接分析推断
16247031 MGI
acts upstream of or within cell migration IMP
IMP: 通过突变表型推断
16247031 MGI
acts upstream of or within cholesterol homeostasis IMP
IMP: 通过突变表型推断
22912762 MGI
acts upstream of or within cholesterol metabolic process IMP
IMP: 通过突变表型推断
22912762 MGI
acts upstream of or within chondrocyte proliferation IMP
IMP: 通过突变表型推断
24550287 MGI
acts upstream of or within embryo implantation IMP
IMP: 通过突变表型推断
20018910 MGI
acts upstream of or within epidermal growth factor receptor signaling pathway IDA
IDA: 通过直接分析推断
19683494 MGI
acts upstream of or within epidermal growth factor receptor signaling pathway IMP
IMP: 通过突变表型推断
22136853 MGI
acts upstream of or within epithelial cell proliferation IMP
IMP: 通过突变表型推断
25976672 MGI
acts upstream of or within epithelium development IMP
IMP: 通过突变表型推断
16819504 MGI
acts upstream of or within fat pad development IMP
IMP: 通过突变表型推断
28053990 MGI
acts upstream of or within gene expression IGI
IGI: 通过遗传相互作用推断
20418913 MGI
acts upstream of or within gene expression IMP
IMP: 通过突变表型推断
19439667 MGI
acts upstream of or within glucose metabolic process IMP
IMP: 通过突变表型推断
28053990 MGI
acts upstream of or within limb joint morphogenesis IMP
IMP: 通过突变表型推断
24550287 MGI
acts upstream of or within lipid metabolic process IMP
IMP: 通过突变表型推断
22912762 MGI
acts upstream of or within liver development IMP
IMP: 通过突变表型推断
22912762 MGI
involved in lung alveolus development IMP
IMP: 通过突变表型推断
19710174 MGI
involved in lung epithelium development IMP
IMP: 通过突变表型推断
19710174 MGI
involved in lung vasculature development IMP
IMP: 通过突变表型推断
19710174 MGI
involved in negative regulation of epidermal growth factor receptor signaling pathway IMP
IMP: 通过突变表型推断
19710174 MGI
involved in negative regulation of epidermal growth factor-activated receptor activity IMP
IMP: 通过突变表型推断
16648858 MGI
acts upstream of or within negative regulation of protein kinase activity by regulation of protein phosphorylation IGI
IGI: 通过遗传相互作用推断
20418913 MGI
acts upstream of or within phosphatidylinositol 3-kinase/protein kinase B signal transduction IMP
IMP: 通过突变表型推断
29843645 MGI
acts upstream of or within progesterone receptor signaling pathway IMP
IMP: 通过突变表型推断
25976672 MGI
acts upstream of or within protein localization to plasma membrane IMP
IMP: 通过突变表型推断
22136853 MGI
acts upstream of or within protein phosphorylation IDA
IDA: 通过直接分析推断
29843645 MGI
acts upstream of or within protein phosphorylation IMP
IMP: 通过突变表型推断
22136853 MGI
involved in regulation of keratinocyte differentiation IMP
IMP: 通过突变表型推断
16648858 MGI
acts upstream of or within regulation of protein binding IDA
IDA: 通过直接分析推断
29843645 MGI
acts upstream of or within regulation of protein tyrosine kinase activity IDA
IDA: 通过直接分析推断
22975324 MGI
acts upstream of or within regulation of signaling receptor activity IMP
IMP: 通过突变表型推断
20018910 MGI
acts upstream of or within response to 1-oleoyl-sn-glycerol 3-phosphate IDA
IDA: 通过直接分析推断
19683494 MGI
acts upstream of or within response to estradiol IDA
IDA: 通过直接分析推断
20018910 MGI
acts upstream of or within response to insulin IMP
IMP: 通过突变表型推断
28053990 MGI
acts upstream of or within response to progesterone IDA
IDA: 通过直接分析推断
20018910 MGI
acts upstream of or within response to progesterone IMP
IMP: 通过突变表型推断
25976672 MGI
acts upstream of or within response to steroid hormone IMP
IMP: 通过突变表型推断
19439667 MGI
acts upstream of or within response to xenobiotic stimulus IDA
IDA: 通过直接分析推断
19683494 MGI
acts upstream of or within skeletal system development IMP
IMP: 通过突变表型推断
17987665 MGI
acts upstream of or within skin development IMP
IMP: 通过突变表型推断
17987665 MGI
involved in skin morphogenesis IMP
IMP: 通过突变表型推断
16648858 MGI
acts upstream of or within tissue homeostasis IMP
IMP: 通过突变表型推断
19439667 MGI
acts upstream of or within uterine epithelium development IMP
IMP: 通过突变表型推断
19439667 MGI
acts upstream of or within uterus development IMP
IMP: 通过突变表型推断
17987665 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
16648858 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
16648858 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ERBB receptor feedback inhibitor 1

mitogen-inducible gene 6 protein homolog

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04516 ERRFI1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19775 Errfi1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26272 Errfi1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Errfi1 NCBI NCBI:54206
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