1. Gene
  2. Sgms2 - sphingomyelin synthase 2 Gene

Sgms2 - sphingomyelin synthase 2 Gene

种属: Mus musculus

同用名: 4933405A16Rik; 5133401H06Rik

基因 ID: 74442 | 基因类型: protein coding

关于 Sgms2

功能概要

Sphingomyelin, a major component of cell and Golgi membranes, is made by the transfer of phosphocholine from phosphatidylcholine onto ceramide, with diacylglycerol as a side product. The protein encoded by this gene is an enzyme that catalyzes this reaction primarily at the cell membrane. The synthesis is reversible, and this enzyme can catalyze the reaction in either direction. The encoded protein is required for cell growth. [provided by RefSeq, Oct 2008]

Sgms2 基因产物(7)

mRNA Protein Name
NM_001379582.1 NP_001366511.1 phosphatidylcholine:ceramide cholinephosphotransferase 2
NM_001379583.1 NP_001366512.1 phosphatidylcholine:ceramide cholinephosphotransferase 2
NM_001379584.1 NP_001366513.1 phosphatidylcholine:ceramide cholinephosphotransferase 2
NM_001379585.1 NP_001366514.1 phosphatidylcholine:ceramide cholinephosphotransferase 2
NM_001379586.1 NP_001366515.1 phosphatidylcholine:ceramide cholinephosphotransferase 2
NM_001379587.1 NP_001366516.1 phosphatidylcholine:ceramide cholinephosphotransferase 2
NM_028943.6 NP_083219.2 phosphatidylcholine:ceramide cholinephosphotransferase 2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ceramide phosphoethanolamine synthase activity IMP
IMP: 通过突变表型推断
25605874 MGI
enables sphingomyelin synthase activity IDA
IDA: 通过直接分析推断
27892528 MGI
enables sphingomyelin synthase activity IMP
IMP: 通过突变表型推断
25667419 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within ceramide biosynthetic process IMP
IMP: 通过突变表型推断
25605874 MGI
acts upstream of or within ceramide phosphoethanolamine biosynthetic process IMP
IMP: 通过突变表型推断
25667419 MGI
acts upstream of or within sphingomyelin biosynthetic process IMP
IMP: 通过突变表型推断
25667419 MGI
involved in sphingomyelin biosynthetic process IMP
IMP: 通过突变表型推断
27892528 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

phosphatidylcholine:ceramide cholinephosphotransferase 2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sgms2 NCBI NCBI:166929