1. Gene
  2. Trim2 - tripartite motif-containing 2 Gene

Trim2 - tripartite motif-containing 2 Gene

种属: Mus musculus

同用名: narf; mKIAA0517

基因 ID: 80890 | 基因类型: protein coding

关于 Trim2

功能概要

Enables ubiquitin protein Ligase activity. Involved in regulation of neuron apoptotic process. Acts upstream of or within cellular response to Leukemia Inhibitory Factor. Predicted to be located in cytoplasm. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 2R. Orthologous to human TRIM2 (tripartite motif containing 2). [provided by Alliance of Genome Resources, Apr 2022]

Trim2 基因产物(5)

mRNA Protein Name
NM_001271725.1 NP_001258654.1 tripartite motif-containing protein 2 isoform 1
NM_001271726.1 NP_001258655.1 tripartite motif-containing protein 2 isoform 2
NM_001271727.1 NP_001258656.1 tripartite motif-containing protein 2 isoform 2
NM_001271728.1 NP_001258657.1 tripartite motif-containing protein 2 isoform 2
NM_030706.3 NP_109631.2 tripartite motif-containing protein 2 isoform 3
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
11432975 MGI
enables ubiquitin protein ligase activity IDA
IDA: 通过直接分析推断
18687884 MGI
enables ubiquitin-protein transferase activity IDA
IDA: 通过直接分析推断
18687884 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: 通过表达模式推断
20439489 MGI
involved in regulation of neuron apoptotic process IMP
IMP: 通过突变表型推断
18687884 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

tripartite motif-containing protein 2

E3 ubiquitin-protein ligase TRIM2

RING-type E3 ubiquitin transferase TRIM2

neural activity-related ring finger protein

tripartite motif protein 2

tripartite motif protein TRIM2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Trim2 NCBI NCBI:23321