2. Immunology/Inflammation Stem Cell/Wnt MAPK/ERK Pathway
  3. Interleukin Related ERK
  4. Glutathione trisulfide

Glutathione trisulfide (GSSSG) 是一种强效的神经保护剂，具有抗炎活性。Glutathione trisulfide (GSSSG) 可抑制脂多糖 (LPS) (HY-D1056) 诱导的视网膜色素上皮细胞炎症基因表达，该抑制作用是通过 ERK 信号通路过度激活介导的，且不依赖于 NRF2/HMOX1 通路。Glutathione trisulfide (GSSSG) 可用于神经退行性疾病和缺血性脊髓损伤 (SCI) 的研究。

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Glutathione trisulfide

Glutathione trisulfide Chemical Structure

CAS No. : 32607-79-7

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Glutathione trisulfide 相关抗体

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生物活性

Glutathione trisulfide (GSSSG) is a potent neuroprotective agent with anti-inflammatory activity. Glutathione trisulfide prevents the LPS (HY-D1056)-induced inflammatory gene expression in retinal pigment epithelial cells, which is mediated through hyperactivation of ERK signaling, independent of the NRF2/HMOX1 pathway. Glutathione trisulfide can be used for neurodegenerative diseases and ischemic spinal cord injury (SCI) research[1][2].

IC50 & Target[1]

IL-6

 

IL-1β

 

分子量

644.69

Formula

C20H32N6O12S3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
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参考文献

Glutathione trisulfide 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

Glutathione trisulfide32607-79-7GSSSGInterleukin RelatedERKILExtracellular signal regulated kinasesLPS-induced inflammatoryretinal pigment epithelial cellsERK signalingARPE-19ischemic injuryInhibitorinhibitorinhibit

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