2. Membrane Transporter/Ion Channel
  3. Sodium Channel
  4. Gonyautoxin II

Gonyautoxin II 是一种麻痹性贝类毒素。Gonyautoxin II 能在轴突水平阻断电压门控钠通道 (voltage-gated sodium channels)，阻碍神经冲动的传导。Gonyautoxin II 对小鼠神经母细胞瘤细胞具有杀伤活性。Gonyautoxin II 可用于癌症和神经系统疾病的研究。

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Gonyautoxin II

Gonyautoxin II Chemical Structure

CAS No. : 60508-89-6

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Gonyautoxin II 相关抗体

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  • 生物活性

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生物活性

Gonyautoxin II is a paralytic shellfish poisoning toxin. Gonyautoxin II can block of the voltage-gated sodium channels at axonal level, impeding nerve impulse propagation. Gonyautoxin II has killing activity against mouse neuroblastoma cells. Gonyautoxin II can be used for the researches of cancer and neurological disease[1][2].

分子量

395.35

Formula

C10H17N7O8S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Gonyautoxin II 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Gonyautoxin II60508-89-6Sodium ChannelNa channelsNa+ channelsInhibitorinhibitorinhibit

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