2. Metabolic Enzyme/Protease
  3. Dipeptidyl Peptidase
  4. Gosogliptin hydrochloride

Gosogliptin hydrochloride 是 Gosogliptin (HY-10287) 的盐酸盐。Gosogliptin (PF-00734200) 是一种强效、口服活性的选择性竞争性 DPP-IV 抑制剂，该酶主要负责降解肠促胰岛素肽 GLP-1 和葡萄糖依赖性促胰岛素多肽。Gosogliptin 表现出对血浆 DPP-4 活性的快速且可逆抑制。Gosogliptin 刺激胰岛素分泌并改善葡萄糖耐量。

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Gosogliptin hydrochloride

Gosogliptin hydrochloride Chemical Structure

CAS No. : 869490-47-1

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Gosogliptin hydrochloride 的其他形式现货产品:

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Gosogliptin hydrochloride 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Gosogliptin hydrochloride is the hydrochloride of Gosogliptin (HY-10287). Gosogliptin (PF-00734200) is a potent, orally active, selective, and competitive inhibitor of DPP-IV, the enzyme mainly responsible for the degradation of the incretin peptides GLP-1 and glucose-dependent insulinotropic polypeptide. Gosogliptin demonstrates rapid and reversible inhibition of plasma DPP-4 activity. Gosogliptin stimulates insulin secretion and improves glucose tolerance[1][2].

分子量

439.33

Formula

C17H26Cl2F2N6O
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Gosogliptin hydrochloride 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Gosogliptin869490-47-1Dipeptidyl PeptidaseDPPDPP-IVglucose toleranceGLP-1Inhibitorinhibitorinhibit

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目录号：
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