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  2. DNA/RNA Synthesis Isotope-Labeled Compounds Caspase Apoptosis Drug Metabolite
  3. Hydroquinone-d4

Hydroquinone-d4  (Synonyms: Quinol-d4; 1,4-Benzenediol-d4; 1,4-Dihydroxybenzene-d4; HQ-d4)

目录号: HY-W738413
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Hydroquinone-d4 (Quinol-d4) 是氘代标记的 Hydroquinone (HY-B0951)。Hydroquinone (Quinol; 1,4-Benzenediol) 是一种抗氧化剂,可作为染料、发动机燃料,及油的合成中间体。Hydroquinone 是苯的主要代谢产物。Hydroquinone 可通过造成 DNA 损伤来增强致癌风险。Hydroquinone 促进肿瘤细胞生长并抑制免疫反应。Hydroquinone 通过线粒体凋亡通路 (Caspase 9/3) 诱导中性粒细胞与嗜酸性粒细胞凋亡 (apoptosis)。Hydroquinone 对水生生物的毒性较高,而对细菌和真菌的毒性较小。

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Hydroquinone-d<sub>4</sub>

Hydroquinone-d4 Chemical Structure

CAS No. : 25294-85-3

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Hydroquinone-d4 (Quinol-d4) is the deuterium labeled Hydroquinone (HY-B0951). Hydroquinone (Quinol; 1,4-Benzenediol) is an antioxidant that can be used as a dye, an engine fuel, and a synthetic intermediate in the production of oil. Hydroquinone is a major benzene metabolite. Hydroquinone is able to enhance carcinogenic risk by generating DNA damage. Hydroquinone promotes tumor cell growth and suppresses the immune response. Hydroquinone induces apoptosis in neutrophils and eosinophils via the mitochondrial apoptosis pathway (Caspase 9/3). Hydroquinone shows increased toxicity for aquatic organisms, being less harmful for bacteria and fungi[1].

产品应用

1. 该化合物可作为示踪剂。
2. 该化合物可作为 NMR、GC-MS 或 LC-MS 分析中的内标品,用于定量分析。

体外研究
(In Vitro)

氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而受到关注。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

114.14

Formula

C6H2D4O2

CAS 号
非标记 CAS
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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