1. Anti-infection
  2. Parasite
  3. JPC-3210

JPC-3210 是一种有口服活性的氨甲基苯酚。JPC-3210 具有抗疟活性,平均 IC50 值范围为 2.5 至 19 nM。JPC-3210 的作用机制是抑制血红蛋白消化途径并促进蛋白质翻译调节因子。JPC-3210 可以抑制 CYP2D6CYP3A4 同工酶。JPC-3210 在小鼠模型中可抑制伯氏疟原虫 (P. berghei) 感染。JPC-3210 在体内具有预防保护作用。JPC-3210 可用于疟疾预防方面的研究。

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JPC-3210

JPC-3210 Chemical Structure

CAS No. : 1609655-35-7

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  • 生物活性

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生物活性

JPC-3210 is an orally active aminomethylphenol. JPC-3210 exhibits anti-malarial activity with a mean IC50 ranging from 2.5 to 19 nM. JPC-3210 works by inhibiting the hemoglobin digestion pathway and promoting regulators of protein translation. JPC-3210 can inhibit CYP2D6 and CYP3A4 isozymes. JPC-3210 suppresses P. berghei infection in mice model. JPC-3210 possesses prophylactic protection in vivo. JPC-3210 can be studied in research on malaria prevention[1][2][3].

分子量

398.44

Formula

C21H26F4N2O

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
JPC-3210
目录号:
HY-117599
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