1. Anti-infection
  2. SARS-CoV
  3. Jun11165

Jun11165 是一种 SARS-CoV-2 PLpro 抑制剂 (IC50 ≤ 0.6 μM),其抑制 SARS-CoV-2 的 EC50 值 ≤ 6 μM。Jun11165 可用于病毒感染的研究。

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Jun11165

Jun11165 Chemical Structure

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Jun11165 is a SARS-CoV-2 PLpro inhibitor (IC50 ≤ 0.6 μM), which inhibits SARS-CoV-2 with an EC50 value of ≤ 6 μM. Jun11165 can be used in the research of viral infections[1].

IC50 & Target

IC50: ≤ 0.6 μM (SARS-CoV-2 PLpro)[1]
EC50: ≤ 6 μM (SARS-CoV-2)[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
Vero C1008 CC50
> 30 μM
Compound: Jun11165
Cytotoxicity against African green monkey Vero E6 cells incubated for 48 hrs by neutral red uptake assay
Cytotoxicity against African green monkey Vero E6 cells incubated for 48 hrs by neutral red uptake assay
[PMID: 38065031]
分子量

380.50

Formula

C22H24N2O2S

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Jun11165 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Jun11165
目录号:
HY-157305
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