2. Cell Cycle/DNA Damage Epigenetics
  3. HDAC
  4. LASSBio-1911

LASSBio-1911 是 HDAC6 的有效抑制剂。LASSBio-1911 对肝细胞癌 (HCC) 细胞具有抗肿瘤作用，对正常细胞的影响极小。

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LASSBio-1911

LASSBio-1911 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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Customer Review

LASSBio-1911 相关抗体

Top Publications Citing Use of Products

查看 HDAC 亚型特异性产品:

查看所有亚型
HDAC HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HDAC7 HDAC8 HDAC9 HDAC10 HDAC11 HD1 HD2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

LASSBio-1911 is a potent inhibitor of HDAC6. LASSBio-1911 shows antitumor in hepatocellular carcinoma (HCC) cells with minimal on normal cells[1].

IC50 & Target

HDAC6

 

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HT-144 IC50
21.18 μM
Compound: 3c
Antiproliferative activity against human HT144 cells assessed as reduction in cell viability after 48 hrs by MTS assay
Antiproliferative activity against human HT144 cells assessed as reduction in cell viability after 48 hrs by MTS assay
[PMID: 26705137]
HepG2 IC50
9.48 μM
Compound: 3c
Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTS assay
Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTS assay
[PMID: 26705137]
分子量

326.35

Formula

C17H18N4O3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

LASSBio-1911 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LASSBio-1911LASSBio1911LASSBio 1911HDACHistone deacetylaseshepatocellular carcinoma (HCC)HepG2 cellHep3B cellInhibitorinhibitorinhibit

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产品名称：
LASSBio-1911
目录号：
HY-161854
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