2. Apoptosis
  3. Ferroptosis
  4. LIBX-A403

LIBX-A403 (Compound 21) 是一种酰基辅酶 A 合成酶长链家族成员 4 (ACSL4) 的高选择性抑制剂 (IC50=0.049 μM)。LIBX-A403 阻断 ACSL4 介导的促铁死亡磷脂重塑过程。LIBX-A403 有望用于癌症 (如三阴性乳腺癌) 及神经退行性疾病 (如帕金森病) 的研究。

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LIBX-A403

LIBX-A403 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货
5 mg ￥3600
询问价格 & 货期
10 mg ￥5440
询问价格 & 货期
25 mg 询价 询问价格 & 货期
50 mg 询价 询问价格 & 货期

* Please select Quantity before adding items.

Customer Review

LIBX-A403 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

LIBX-A403 (Compound 21) is a highly selective acyl-CoA synthetase long-chain family member 4 (ACSL4) inhibitor (IC50=0.049 μM). LIBX-A403 blocks ACSL4-mediated ferroptosis-promoting phospholipid remodeling. LIBX-A403 is promising for research of cancers (e.g., triple-negative breast cancer) and neurodegenerative diseases (e.g., Parkinson’s disease)[1].

分子量

363.36

Formula

C21H17NO5
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

LIBX-A403 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LIBX-A403FerroptosisACSL4phospholipid remodelingcancersneurodegenerative diseasesInhibitorinhibitorinhibit

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产品名称：
LIBX-A403
目录号：
HY-175328
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