1. Membrane Transporter/Ion Channel Neuronal Signaling
  2. Calcium Channel
  3. Maitotoxin disodium

Maitotoxin disodium  (Synonyms: 鱼尾素; MTX disodium)

目录号: HY-N11865
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Maitotoxin (MTX) disodium 是一种 Ca2+ 通道激活剂,也是存在于 Ctenochaetus striatus 中的水溶性毒素。Maitotoxin disodium 具有明显的生物毒性。Maitotoxin disodium 可引发猫严重呕吐。Maitotoxin disodium 会导致小鼠活动能力丧失、肢体无力、抽搐乃至死亡。

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Maitotoxin disodium

Maitotoxin disodium Chemical Structure

CAS No. : 59392-53-9

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Maitotoxin (MTX) disodium is a Ca2+ channel activator and a water-soluble toxin present in the Ctenochaetus striatus. Maitotoxin disodium exhibits significant biological toxicity. Maitotoxin disodium induces severe vomiting in cats. Maitotoxin disodium causes loss of mobility, limb weakness, convulsions and even death in mice[1].

体外研究
(In Vitro)

Maitotoxin disodium (10-8 g/mL; 0-8 min) 在大鼠嗜铬细胞瘤 PC12h 细胞中诱导 Ca2+ 内流显著增加且引发 Ca2+ 依赖性的 [3H] 去甲肾上腺素释放[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Maitotoxin disodium 在小鼠中腹腔注射的最小致死剂量为 15~20mg/kg[2]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

3425.86

Formula

C164H256Na2O68S2

CAS 号
中文名称

鱼尾素; 刺尾鱼毒素

初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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