2. Immunology/Inflammation
  3. Interleukin Related
  4. MAS825

MAS825  (Synonyms: Arumakimig)

目录号: HY-P991083 纯度: 95.83%
COA 技术支持

MAS82590 (Arumakimig) 是一种双特异性 IL-1β 和 IL-18 单克隆抗体，可减少炎性体介导的炎症。MAS825 可将抗 IL-1β 和抗 IL-18 单克隆抗体 (mAb) 抑制域结合在单个双特异性高亲和力细胞因子捕获分子中。

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规格 价格 是否有货 数量
1 mg ￥5000
In-stock
5 mg 现货 询价
10 mg   询价  
50 mg   询价  

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MAS825 相关抗体

Top Publications Citing Use of Products

查看 Interleukin Related 亚型特异性产品:

查看所有亚型
IL-1 IL-2 IL-3 IL-4 IL-5 IL-6 IL-8 IL-10 IL-12 IL-13 IL-15 IL-17 IL-23 IL-7 IL-33 IL-22 IL-18

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MAS82590 (Arumakimig) is a bispecific IL-1β and IL-18 monoclonal antibody that reduces inflammasome-mediated inflammation. MAS825 combines the anti-IL-1β and anti-IL-18 monoclonal antibodies (mAbs) inhibition domains in a single bispecific high-affinity cytokine capture molecule[1].

同型

Ig(G1-kappa_G1-lambda2)
推荐同型对照抗体
反应种属

Human
IC50 & Target

IL-1β & IL-18
Clinical Trial
基因 ID

0  [NCBI]

Accession
靶点

IL-1β & IL-18
应用

ELISA, FACS, Functional assay
偶联物

Unconjugated
复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.
分子量

144.353 kDa

性状

液体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
  • Immobilized IL-1 beta Protein, Human (HY-P7028) can bind MAS825. The EC50 for this effect is 3.057 ng/mL.
  • Immobilized IL-18 Protein, Human (HY-P70591) can bind MAS825. The EC50 for this effect is 17.99 ng/mL.
纯度 & 产品资料
参考文献

MAS825 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MAS825ArumakimigMAS 825MAS-825Interleukin RelatedILInhibitorinhibitorinhibit

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目录号：
HY-P991083
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