2. Academic Validation
  3. Novel dammarane-type glycosides from Gynostemma pentaphyllum

Novel dammarane-type glycosides from Gynostemma pentaphyllum

  • Chem Pharm Bull (Tokyo). 2004 Dec;52(12):1440-4. doi: 10.1248/cpb.52.1440.
Feng Yin 1,  Lihong Hu,  Ruixiang Pan
Affiliations

Affiliation

  • 1 National Center for Drug Screening, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 189 Guo-Shou-Jing Road, Shanghai 201203, China.
PMID: 15577241 DOI: 10.1248/cpb.52.1440
Abstract

Three new dammarane glycosides (1-3), together with five known compounds, gypenoside LXIX (4), gylongiposide I (5), gypenoside XLVIII (6), allantion (7) and vitexin (8) were isolated from the MeOH extract of the aerial parts of Gynostemma pentaphyllum. Compounds 5, 7, and 8 were isolated from this plant for the first time. Their structures were elucidated by 1D and 2D NMR spectra interpretation as well as by chemical degradation.

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