2. GPCR/G Protein
  3. Leukotriene Receptor
  4. MDL 43291

MDL 43291 是一种竞争性的白三烯 (leukotriene) 受体拮抗剂。MDL 43291 可拮抗 LTD4 和 LTE4，其 pA2 值均为 6.7。MDL 43291 不会拮抗组胺、卡巴胆碱或 P 物质。MDL 43291 可用于炎症和免疫学研究，如哮喘研究。

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MDL 43291

MDL 43291 Chemical Structure

CAS No. : 129357-91-1

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MDL 43291 相关抗体

Top Publications Citing Use of Products

查看 Leukotriene Receptor 亚型特异性产品:

查看所有亚型
LTB4 LTC4/CysLT2 LTD4/CysLT1 LTE4

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MDL 43291 is a competitive leukotriene (LT) receptor antagonist. MDL 43291 antagonize LTD4 and LTE4 with pA2 of 6.7. MDL 43291 does not antagonize histamine, carbachol or substance P. MDL 43291 can be used for the researches of inflammation and immunology, such as asthma[1].

IC50 & Target[1]

LTD4

6.7 (pA2)

LTE4

6.7 (pA2)

体内研究
(In Vivo)

MDL 43291 (10-30 mg/kg，静脉注射) 能有效抑制豚鼠中由 LTD4 引起的充气压力升高[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

438.66

Formula

C25H42O4S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

MDL 43291 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MDL 43291129357-91-1MDL43291MDL-43291Leukotriene ReceptorLTD4LTE4leukotrieneinflammationimmunologyasthmaInhibitorinhibitorinhibit

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产品名称：
MDL 43291
目录号：
HY-105483
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