1. Metabolic Enzyme/Protease
  2. Carbonic Anhydrase
  3. Mefruside

Mefruside 是一种口服有效的利尿剂,并具有轻微的降压作用。Mefruside 在离体大鼠肝脏灌注模型中能抑制尿素的合成。Mefruside 可用于水肿和高血压的研究。

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Mefruside

Mefruside Chemical Structure

CAS No. : 7195-27-9

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Other Forms of Mefruside:

查看 Carbonic Anhydrase 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Mefruside is an orally active diuretic and has a mild hypotensive effect. Mefruside inhibits the synthesis of urea in an isolated rat liver perfusion model. Mefruside can be used in studies of oedema and hypertension[1][2].

体外研究
(In Vitro)

Mefruside (0.3 mM; 50 min) shows 34% inhibition of urea synthesis in isolated perfused rat liver[1].
Mefruside (0.25, 0.5, 0.75, 1, 1.25 mM) inhibits urea synthesis in a concentration-dependent manner in isolated perfused rat liver[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: Rat liver (from male Wistar rats of 120-220 g body weight; isolated perfused model)
Concentration: 0.3 mM
Incubation Time: 50 min
Result: Exhibited inhibition rate of urea synthesis of 34%.
分子量

382.88

Formula

C13H19ClN2O5S2

CAS 号
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料
参考文献
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  • 稀释计算器

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Mefruside
目录号:
HY-123179
需求量: