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  3. Drug Derivative
  4. Mexiprostil

Mexiprostil (MDL 646) 是一种口服有效的胃保护剂，是一种合成的 Prostaglandin E1 (HY-B0131) 的类似物。Mexiprostil 在大鼠、狗和猫中对 Histamine (HY-B1204) 和 Bethanechol (HY-B0406) 引起的胃酸分泌有显著的抑制作用。Mexiprostil 在猫中还能抑制 Pentagastrin (HY-A0261) 引起的胃酸分泌增多，在狗和大鼠中则不能。Mexiprostil 未引起妊娠终止。Mexiprostil 可用于研究胃溃疡。

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Mexiprostil

Mexiprostil Chemical Structure

CAS No. : 88980-20-5

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Mexiprostil 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Mexiprostil (MDL 646) is an orally active gastric protectant, being a synthetic analogue of Prostaglandin E1 (HY-B0131). Mexiprostil exhibits significant inhibition of gastric acid secretion caused by Histamine (HY-B1204) and Bethanechol (HY-B0406) in rats, dogs, and cats. Mexiprostil can also inhibit the increase in gastric acid secretion caused by Pentagastrin (HY-A0261) in cats, while it does not have this effect in dogs and rats. Mexiprostil does not cause pregnancy termination. Mexiprostil can be used for research on gastric ulcers[1][2].

分子量

412.56

Formula

C23H40O6
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Mexiprostil 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Mexiprostil88980-20-5MDL 646MDL646MDL-646Drug DerivativeDrug derivativeLuteolytic ActivityProstaglandin AnalogueHamster ModelAntifertility EffectsProgesterone LevelsGastroprotective SpecificityStructure-Activity RelationshipInhibitorinhibitorinhibit

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