2. GPCR/G Protein Neuronal Signaling
  3. Dopamine Receptor
  4. (-)-MDO-NPA

(-)-MDO-NPA 是一种 N-丙基去甲阿扑吗啡类似物和 D1R/D2R 双靶点配体。(-)-MDO-NPA 对 β-arrestin 的 EC50 为 1949 nM (D1R) 和 520 nM (D2R)。(-)-MDO-NPA 对 cAMP 的 EC50 为 717.5 nM (D1R) 和 7.7 nM (D2R)。(-)-MDO-NPA 可用于帕金森病等多巴胺相关疾病的研究。

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(-)-MDO-NPA

(-)-MDO-NPA Chemical Structure

CAS No. : 81264-57-5

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(-)-MDO-NPA 相关抗体

Top Publications Citing Use of Products

查看 Dopamine Receptor 亚型特异性产品:

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Dopamine Receptor D1 Receptor D2 Receptor D3 Receptor D4 Receptor D5 Receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(-)-MDO-NPA is an N-propylnorapomorphine analog and a D1R/D2R dual-target ligand. (-)-MDO-NPA has EC50 values of 1949 nM (D1R) and 520 nM (D2R) for β-arrestin. (-)-MDO-NPA has EC50 values of 717.5 nM (D1R) and 7.7 nM (D2R) for cAMP. (-)-MDO-NPA can be used in the research of dopamine-related diseases such as Parkinson’s disease[1].

分子量

307.39

Formula

C20H21NO2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

(-)-MDO-NPA 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(-)-MDO-NPA81264-57-5Dopamine ReceptorPDInhibitorinhibitorinhibit

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