2. Antibody-drug Conjugate/ADC Related Immunology/Inflammation Apoptosis
  3. Antibody-Drug Conjugates (ADCs) CD276/B7-H3 Bcl-2 Family
  4. Mirzotamab clezutoclax

Mirzotamab clezutoclax  (Synonyms: ABBV-155)

目录号: HY-P99741
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Mirzotamab clezutoclax (ABBV-155) 是一种首创的抗体药物偶联物 (ADC)，由三种成分组成：抗 B7-H3 单克隆抗体和 BCL2L1 (BCL-XL) 抑制剂 Clezutoclaxum (HY-137774)。Mirzotamab clezutoclax 可用于复发和/或难治性 (R/R) 实体瘤的研究。

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Mirzotamab clezutoclax

Mirzotamab clezutoclax Chemical Structure

CAS No. : 2229859-12-3

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Mirzotamab clezutoclax 相关抗体

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查看 Bcl-2 Family 亚型特异性产品:

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Bcl-2 Bcl-xL Bcl-W Mcl-1 Bfl-1 Bcl-B Bax Bak Bim BNIP3

  • 生物活性

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生物活性

Mirzotamab clezutoclax (ABBV-155) is a first-in-class antibody-drug conjugate (ADC) with three components: an anti-B7-H3 monoclonal antibody, and BCL2L1 (BCL-XL) inhibitor Clezutoclaxum (HY-137774). Mirzotamab clezutoclax can be used for the study of relapsed and/or refractory (R/R) solid tumors[1].

IC50 & Target[1]

Bcl-xL

 

CD267/B7-H3

 

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Mirzotamab clezutoclax 相关分类

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Mirzotamab clezutoclax2229859-12-3ABBV-155ABBV155ABBV 155Antibody-Drug Conjugates (ADCs)CD276/B7-H3Bcl-2 FamilyAntibody-Drug ConjugatesB7 homolog 3 proteinInhibitorinhibitorinhibit

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