2. Metabolic Enzyme/Protease
  3. Mitochondrial Metabolism
  4. MitoBloCK-1

MitoBloCK-1 (MB-1) 是一种抑制剂，可以阻断利用 TIM22 输入途径的底物输入。MitoBloCK-1 通过阻止底物与 tim9/10 复合物结合来抑制底物转运，从而使底物无法到达 TIM22 转运蛋白。MitoBloCK-1 抑制 TIM22 底物蛋白导入线粒体 (mitochondria)。MitoBloCK-1 可减弱包括 ADP/ATP 和磷酸盐载体在内的载体蛋白的转运。MitoBloCK-1 还能抑制另一种载体蛋白 PiC 和外膜蛋白 Tom40 的转运。

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MitoBloCK-1

MitoBloCK-1 Chemical Structure

CAS No. : 373370-73-1

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规格 价格 是否有货 数量
1 mg ￥3110
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MitoBloCK-1 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MitoBloCK-1 (MB-1) is an inhibitor that blocks the import of substrates that use the TIM22 import pathway. MitoBloCK-1 inhibits import by preventing binding of substrate to tim9/10 complex to the substrate, thus the substrate failed to be reach the TIM22 translocon. MitoBloCK-1 inhibits protein import of TIM22 substrates into mitochondria. MitoBloCK-1 attenuates the import of the carrier proteins including the ADP/ATP and phosphate carriers. MitoBloCK-1 also inhibits the import of an additional carrier protein, PiC, and the outer membrane protein Tom40[1][2].

分子量

368.25

Formula

C14H14BrN3O2S
CAS 号
性状

固体

颜色

Off-white to light yellow

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料
参考文献

MitoBloCK-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MitoBloCK-1373370-73-1MB-1MitoBloCK1MitoBloCK 1MB1MB 1Mitochondrial MetabolismInhibitorinhibitorinhibit

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目录号：
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