2. Cell Cycle/DNA Damage Metabolic Enzyme/Protease
  3. ClpP Mitochondrial Metabolism
  4. MS6076

MS6076 是一种线粒体蛋白酶 ClpP 激动剂。MS6076 特异性激活线粒体基质中的 ClpP 蛋白酶，通过加速未折叠蛋白的降解，显著破坏线粒体电子传递链 (ETC) 功能。MS6076 对多种乳腺癌细胞系表现出强效的细胞毒性，包括三阴性乳腺癌细胞 (MDA-MB-468、MDA-MB-231) 及其他亚型 (SK-BR-3、MCF-7、BT-474)。MS6076 可用于乳腺癌研究。

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MS6076

MS6076 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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Customer Review

MS6076 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MS6076 is a mitochondrial protease ClpP agonist. MS6076 specifically activates the ClpP protease in the mitochondrial matrix, significantly disrupting mitochondrial Electron Transport Chain (ETC) function by accelerating the degradation of unfolded proteins. MS6076 exhibits potent cytotoxicity against a variety of breast cancer cell lines, including triple-negative breast cancer cells (MDA-MB-468, MDA-MB-231) and other subtypes (SK-BR-3, MCF-7, BT-474). MS6076 can be used for the study of breast cancer[1].

分子量

524.54

Formula

C27H27F3N6O2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

MS6076 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MS6076MS 6076MS-6076ClpPMitochondrial MetabolismCaseinolytic protease PMDA-MB-468MDA-MB-231SK-BR-3MCF-7BT-474breast cancermitochondrial Electron Transport ChainInhibitorinhibitorinhibit

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产品名称：
MS6076
目录号：
HY-178749
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