2. Metabolic Enzyme/Protease
  3. Glycosidase
  4. N-Octyl-α-4-epivalienamine

N-Octyl-α-4-epivalienamine 是一种口服有效且能可穿透血脑屏障的分子伴侣，可诱导缺陷型 β-半乳糖苷酶 (β-galactosidase) 活性的高表达。N-Octyl-α-4-epivalienamine 可改善 GM1 神经节苷脂沉积症小鼠模型的症状并提高其存活率。N-Octyl-α-4-epivalienamine 可用于神经遗传疾病的研究。

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N-Octyl-α-4-epivalienamine

N-Octyl-α-4-epivalienamine Chemical Structure

CAS No. : 942065-96-5

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N-Octyl-α-4-epivalienamine 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

N-Octyl-α-4-epivalienamine is an orally active and CNS-penetrant molecular chaperone that induces high expression of the deficient β-galactosidase activity. N-Octyl-α-4-epivalienamine ameliorates symptoms and increase survival rate in a mouse model of GM1-gangliosidosis. N-Octyl-α-4-epivalienamine can be used for neurogenetic disease research[1].

IC50 & Target[1]

β-galactosidase

 

分子量

287.40

Formula

C15H29NO4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

N-Octyl-α-4-epivalienamine 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N-Octyl-α-4-epivalienamine942065-96-5Glycosidaseβ-galactosidase activitydeficient β-galactosidase activitymouse model of GM1-gangliosidosisInhibitorinhibitorinhibit

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